ESSENTIAL HYPERTENSION

This study tested whether taking two experimental drugs together (BR1018B and BR1018C) can safely lower both blood pressure and LDL cholesterol in people with essential hypertension and primary hypercholesterolemia. A total of 156 adults participated. The main goals were to see h…

This study looked at whether a plant-based omega-3 supplement can improve blood vessel function in people with high blood pressure and metabolic syndrome. About 95 adults with treated hypertension and at least two signs of metabolic syndrome took part. Researchers measured change…

This study tested whether regularly warming the lower legs in warm water (about 107°F) could help lower blood pressure in older women with hypertension. 134 women aged 60-85 took part, all also taking a standard blood pressure pill. The goal was to see if adding heat therapy to m…

This study tested whether adding a third drug (DWC202314) to a two-drug combination (DWC202405/DWC202313) helps lower blood pressure more effectively in people whose high blood pressure is not well controlled with the two-drug combo alone. The trial involved 198 adults with essen…

This study tested whether adding a second drug (DWC202314) to an existing one (DWC202404) helps lower blood pressure in people whose hypertension is not well controlled with the first drug alone. 192 adults with essential hypertension took part. The main goal was to see how much …

This study tested whether taking two blood pressure medicines together works better than taking either one alone. About 890 adults with mild-to-moderate high blood pressure took part. The goal was to see if the combination lowers blood pressure more effectively and safely over 8 …

This study looked at whether a new blood marker called EM66 can help doctors tell the difference between high blood pressure caused by rare adrenal tumors (pheochromocytoma or paraganglioma) and regular high blood pressure. Researchers measured EM66 levels in 60 adults with suspe…

This study looked at whether adding paced or diaphragmatic breathing to mat Pilates helps people with stage II hypertension feel less stressed and anxious, and improves their heart and lung fitness. Sixty-three adults aged 40 to 50 took part in six weeks of supervised sessions. T…

This study tested whether a brief sleep hygiene education session could improve sleep quality and blood pressure in adults with high blood pressure. 138 participants were randomly assigned to receive the education or usual care. After 8 weeks, researchers measured changes in slee…

This study looked at how blood pressure medications affect brain blood flow and thinking skills in older adults with high blood pressure. Researchers gave 27 participants either a drug or a placebo for 1-2 weeks and measured brain blood flow, nerve activity, and cognitive perform…

This early-stage study tested a new drug called BR1018, along with two other drugs (BR1018A and BR1018B), in 60 healthy adults. The goal was to see how the drugs move through the body and to check for any safety issues. The study is now complete and helps researchers understand h…

This study tested whether a ketone supplement could improve kidney function and blood pressure in 20 people with high blood pressure. Participants took either the ketone drink or a placebo for 5 days, then switched after a break. Researchers measured blood pressure, kidney blood …