Exercise may boost brain health in seniors with high blood pressure
NCT ID NCT05043454
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small pilot study looked at whether a short exercise program could help older adults (ages 55-75) with high blood pressure improve their thinking skills. Researchers measured changes in fitness, eye blood vessels, and blood markers. The goal was to see if exercise might reverse some age-related cognitive decline.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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11 people
The number who actually took part.
- Started
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Oct 2021
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * adults between 55-75 years of age * essential hypertension (as determined by referring physicians) * engages in less than 150 minutes of moderate intensity exercise/week (as determined by CHAMPS Questionnaire) * physically able to exercise * access to an upright cycle ergometer at home or via gym access * access to smart device (iOS or Android phone or tablet with ability to install and use Polar Beat and Polar FlowTM applications). Exclusion Criteria: * diagnosis of dementia * resting systolic blood pressure \<120, or \>180 mm Hg * disease or condition that would preclude exercise * untreated depression or anxiety disorders * severe respiratory disease * disease of the eye * refractive error \> 6 diopters or +6 diopters (as assessed by 1st retinal scan).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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Other studies related to the condition(s) this trial covers.
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