COVID-19

This study tested a new mRNA vaccine designed to protect against COVID-19 in 182 healthy adults aged 18 and older. The main goals were to check the vaccine's safety and measure the immune response it produced. The trial was stopped early, so results are limited, but it aimed to f…

This study aimed to measure how effective the 2024-2025 Pfizer COVID-19 vaccine is at preventing symptomatic infection in real-world settings. Researchers planned to compare vaccinated and unvaccinated people who got tested for COVID-19 at CVS MinuteClinics. The study was termina…

This study tested a single dose of two lab-made antibodies (casirivimab+imdevimab) given through a vein to children hospitalized with COVID-19. The goal was to see how the drug moves in the body and if it is safe. Only 2 children took part before the study was stopped early, so r…

This study tested an experimental drug called ABX464 in 509 older adults (65+) and younger people with risk factors like obesity or diabetes who had COVID-19. The goal was to see if the drug could reduce inflammation and prevent severe breathing problems that require a breathing …

This study aimed to see if hydroxychloroquine could help hospitalized COVID-19 patients recover faster. It planned to enroll 350 adults but was stopped early after only 17 joined. Participants received either hydroxychloroquine plus usual care or usual care alone for five days, a…

This study tested an intranasal spray called AD17002 in adults aged 18 to 65 with mild to moderate COVID-19. Participants received standard care plus either a placebo or one of two doses of the spray. The goal was to see if the spray could speed up recovery and improve symptoms. …

This study tested whether a low dose of tocilizumab, a drug used for arthritis, could help hospitalized COVID-19 patients with lung inflammation recover faster. It included 85 adults who were not on a breathing machine. The trial was stopped early, but the results may help guide …

This study tested whether imatinib, a cancer drug, could help hospitalized adults with COVID-19. It was a Phase 3 trial that planned to compare imatinib plus standard care to a placebo plus standard care, but it was stopped early after enrolling only 21 people. The main goal was …

This study tested whether tocilizumab, an anti-inflammatory drug, could help hospitalized adults with severe COVID-19. It aimed to compare the drug to a placebo in about 300 people, but was stopped early after enrolling only 20 participants. The main goal was to see if the drug i…

This study tested whether stem cells from donated fat tissue could help people with COVID-19. Participants received four infusions of either the stem cells or a placebo. The trial was stopped early and involved 48 adults suspected of having COVID-19.

This study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes, high blood pressure, or obesity. The goal was to see if the drug could prevent death, ICU admission, or heart complications. The trial was stop…

This study tested a medicine called ensovibep in adults with mild-to-moderate COVID-19 who were not in the hospital. The goal was to see if it could lower the amount of virus in the body and reduce the need for hospital care. About 400 people took part, but the study was stopped …

This study tested a drug called INB03 (XPro1595) to see if it could stop COVID-19 patients from developing serious lung complications. The trial included 79 high-risk adults (e.g., over 65, obese, or with conditions like diabetes or heart disease). The study was terminated early,…

This study tested whether the drug aprepitant, given as an injection, could help hospitalized adults with COVID-19 recover faster. The trial was stopped early after enrolling only 27 participants. The goal was to see if the drug reduced the need for breathing support and shortene…

This study tested whether giving plasma (the liquid part of blood) from people who recovered from COVID-19 could help hospitalized patients with moderate to severe COVID-19 get better faster. The trial planned to enroll many adults, but was stopped early after including 102 parti…

This study tested an antiviral drug called ensitrelvir in adults hospitalized with COVID-19. The goal was to see if adding this drug to standard care helped patients recover faster. The trial was stopped early and involved about 600 participants worldwide.

This study tested a single injection of two lab-made antibodies (casirivimab and imdevimab) in children under 12 who are at high risk for severe COVID-19. The goal was to see how the antibodies behave in the body, check for side effects, and measure immune response. Only 7 childr…

This study looked at using a fast, point-of-care COVID-19 test to help triage patients with heart or breathing emergencies. Researchers tested 66 adults who already had COVID-19 to see if the rapid test gave the same results as standard lab tests. They also compared different swa…

This study tested a new touchless camera that analyzes sweat from fingerprints to quickly detect COVID-19. Researchers enrolled 66 adults who had tested positive or negative for COVID-19 within the past week. The goal was to see if sweat markers could distinguish between infected…

This study tested whether a daily pill (TAF/FTC), normally used for HIV, could prevent COVID-19 in healthcare workers at high risk of exposure. About 1,378 participants were randomly assigned to receive the drug or a placebo. The trial was terminated early, and the results did no…

This study aimed to see if emetine, an older drug, could help adults with mild-to-moderate COVID-19 feel better faster and avoid hospitalization. Participants took emetine pills or a placebo for 10 days. However, the trial was stopped early after enrolling only 4 people, so no me…

This study looked at whether a supervised exercise and breathing program could help people with Long COVID feel better and move more easily. Researchers measured changes in fitness, fatigue, and quality of life in 21 adults who had COVID at least 12 weeks earlier. The program aim…

This study looked at how COVID-19 impacts people with cancer. Researchers measured how many cancer patients had COVID-19 without symptoms and how their immune systems responded. The study included 83 participants but was stopped early.

This study looked at whether virtual coaching helps rural pharmacists better counsel patients who are hesitant about COVID-19 vaccines. Sixteen pharmacies took part, first receiving standard training and then adding a virtual coach. Researchers measured how well pharmacists commu…

This study tested a special band called AirGo that monitors breathing in COVID-19 patients with respiratory failure. The goal was to see if the band could detect early signs of worsening breathing. The study included 25 adults hospitalized with COVID-19 who were breathing on thei…