COGNITIVE DYSFUNCTION

This study tested an artificial intelligence platform that screens for cognitive issues like dementia by analyzing how people move their eyes. Over 1,500 participants, including those with normal cognition and various types of dementia, took part. The goal was to see how accurate…

This study looked at whether a home-based physical activity program and computer-based cognitive training could help prevent memory loss in older women with heart disease. Researchers enrolled 253 women aged 65 and older with a history of cardiovascular disease who were not alrea…

This study tested if a noninvasive brain stimulation technique called repetitive Transcranial Magnetic Stimulation (rTMS) could improve memory in people with mild cognitive impairment (MCI). 69 participants were randomly assigned to receive active rTMS to one of two brain areas o…

This study tested whether a program that combines talk therapy, brain training exercises, and healthy lifestyle coaching is practical and helpful for people with mild cognitive impairment, traumatic brain injury, multiple sclerosis, or long COVID. Fifteen participants received th…

This study tested whether an 8-week mindfulness program could reduce anxiety in 168 older adults who worry about their memory but still score normally on memory tests. Participants were randomly assigned to either mindfulness training or a health education program. The goal was t…

This study tested a training program for people with mild to moderate Alzheimer's disease. The training used personal photos and videos to recreate familiar situations, aiming to improve orientation to time, place, and person. 126 participants were assigned to either the training…

This early study tested a drug called SAGE-718 in 18 people with Parkinson's disease who also have mild problems with memory and thinking. The main goal was to see if the drug is safe and tolerable. Researchers also looked at whether it helped with thinking, mood, and movement. T…

This study tested whether using EEG brain-wave monitoring during anesthesia helps doctors give the right amount of medicine, so patients wake up faster after surgery. About 100 adults having general anesthesia took part. Researchers also checked if this approach reduces short-ter…

This study tested a new exercise device called FitMi AD in 31 people with mild cognitive impairment or mild dementia due to Alzheimer's disease. The device uses sensors to track movements while users follow exercises shown on a computer screen. The goal was to see if it could imp…

This study tested whether turning-based dual-task training (exercises that combine movement and thinking) could improve balance and mild cognitive issues in 50 adults with diabetic peripheral neuropathy. Participants were aged 50 and older and had both balance problems and mild c…

This study looked at whether digital or physical brain exercises could help older adults with mild to moderate Alzheimer's disease. Over 500 people in Portugal took part. The goal was to see if these activities could improve memory, thinking, mood, and quality of life.

This study tested whether adding structured supportive psychotherapy to the medication risperidone helps improve thinking and reduce inflammation in people with schizophrenia. Forty-six men took part, with half receiving both therapy and medication, and the other half receiving m…

This study tested whether a nerve block called stellate ganglion block (SGB), given with standard medication, could improve thinking and memory in people with Alzheimer's disease. Forty participants were randomly assigned to receive either SGB plus standard drugs or standard drug…

This study tested a new drug called SAGE-718 in 26 people with mild memory or thinking problems due to Alzheimer's disease. The main goal was to see if the drug is safe and tolerable, and to check if it helps with cognitive and mood symptoms. Participants took the drug and were m…

This study tested a 12-week intensive aerobic and resistance exercise program in 58 adults aged 40-85 with type 2 diabetes and thinking problems. The goal was to see if exercise could improve memory, metabolism, inflammation, and physical function. Participants were grouped by ri…

This study tested whether a special magnetic device, used at home, could help people with long COVID who have trouble thinking clearly (brain fog). Thirty adults used the device for 4 weeks and were then followed for another 4 weeks. The main goal was to see if the device was eas…

This study tested an experimental drug called SAGE-718 to see if it could improve thinking and memory in people with Parkinson's disease who have mild cognitive impairment. 86 participants took either the drug or a placebo. The main goal was to measure changes in processing speed…

This study looked at whether shining a special light on the head (called transcranial photobiomodulation) can improve blood flow in the brain and help with thinking skills. Researchers tested 24 adults aged 18 to 80. The goal was to understand how the light affects brain health, …

This study looked at 134 adults with chronic sinusitis to see if sleep problems and daytime tiredness predict worse thinking and daily function. Participants filled out questionnaires about their symptoms and quality of life. The goal was to better understand how sinusitis affect…

This study placed 15 healthy adults in a cave for 40 days with no clocks or sunlight to see how their bodies and minds adapt. Researchers measured changes in sleep, stress, thinking, and how the group worked together. The goal was to understand how extreme isolation and lack of t…

This study looked at whether continuously measuring oxygen levels in the brain during heart bypass surgery can help prevent memory loss and confusion afterward. It included 326 adults aged 60 and older having planned coronary artery bypass surgery. Researchers compared standard c…

This study looked at whether a 30-minute walk outside in a green area helps people recover from mental tiredness and stress better than walking on a treadmill indoors. Researchers split 80 healthy young adults into two groups: one walked outdoors in nature, the other walked on a …

This study looked at 102 adults having planned heart surgery to see if drops in brain oxygen levels during the operation are linked to memory or thinking problems afterward. Researchers measured brain oxygen with a special monitor and tested thinking skills before and after surge…