COGNITIVE DYSFUNCTION

This study tested whether a 12-week intensive exercise program could improve brain function and overall health in middle-aged and older adults with type 2 diabetes. Researchers enrolled 58 participants, assigning some to the exercise program and others to continue their usual car…

This study tested if a temporary nerve-blocking injection in the neck, given alongside standard Alzheimer's medications, could help improve thinking, memory, and daily life for people with the disease. Researchers compared two groups over six months: one received the injection pr…

This small study tested whether adding structured supportive talk therapy to standard schizophrenia medication (risperidone) could improve thinking skills and reduce body inflammation better than medication alone. It involved 46 men with recent schizophrenia diagnoses over 6 week…

This study tested whether using a special monitor to track oxygen levels in the brain during heart bypass surgery could help prevent memory and thinking problems after the operation. Researchers enrolled 326 patients aged 60 and older. They compared standard care to using the mon…

This study tested whether a 24-week program of home-based physical activity and computer brain training could help prevent or delay memory loss in older women with heart disease. Researchers enrolled 253 women aged 65 and older to compare different combinations of the exercise an…

This study tested whether an investigational drug called SAGE-718 could improve cognitive performance, specifically processing speed, in people with Parkinson's disease who have mild thinking problems. 86 participants were randomly assigned to receive either the drug or a placebo…

This study tested the safety and side effects of an investigational drug called SAGE-718 in people with early Alzheimer's disease or mild cognitive impairment. It involved 26 participants and aimed to see if the drug was well-tolerated while also checking for any effects on memor…

This small pilot study tested whether a personalized program combining different types of therapy and lifestyle advice is practical and helpful for people with conditions affecting thinking and memory, like brain injuries or multiple sclerosis. Fifteen participants were randomly …

This study tested whether a new computer-guided exercise device could help people with early Alzheimer's disease or mild memory problems. The device, called FitMi AD, uses sensors to track movements while users follow exercises shown on a screen. Researchers wanted to see if usin…

This study tested whether a noninvasive brain stimulation technique could improve memory in older adults with mild cognitive impairment. Participants received either active magnetic stimulation to specific brain areas or a placebo treatment over several weeks. Researchers measure…

This study tested the safety and side effects of an experimental drug called SAGE-718 in people with Parkinson's disease who have mild thinking and memory problems. Eighteen participants with early to moderate Parkinson's took the drug to see how well they tolerated it and whethe…

This study tested whether closely monitoring a patient's brain waves (EEG) during general anesthesia helps doctors give the right amount of sleep medicine. Researchers wanted to see if this personalized approach helps patients wake up faster after surgery and reduces problems wit…

This small, completed study tested whether a magnetic therapy device could be used safely and easily at home by people with Long COVID brain fog. It involved 30 adults who had experienced cognitive problems for at least six months after a COVID-19 infection. The main goal was to …

This study tested whether an 8-week mindfulness course could reduce anxiety and improve mental wellbeing in older adults who are worried about their memory but still test normally. Researchers compared the mindfulness program to a health education course in 168 participants acros…

This study tested whether walking in a green outdoor space helps people bounce back from mental tiredness and stress better than walking indoors. Researchers had 80 healthy young adults take a 30-minute walk, either outside in a forest park or inside on a treadmill in a plain roo…

This study looked at whether poor sleep and daytime tiredness in people with chronic sinusitis (CRS) can predict problems with memory, concentration, and daily activities. Researchers surveyed 134 adult patients with long-term sinus symptoms using questionnaires about their sleep…

This study aimed to understand how a non-invasive light therapy, called transcranial photobiomodulation, affects brain blood vessel health and cognitive function like memory and thinking. It involved 24 adults aged 18-80 who received up to eight light therapy sessions over four w…

This study looked at whether drops in brain oxygen levels during heart surgery are connected to memory and thinking problems that can happen after the operation. Researchers monitored 102 adult patients having planned heart surgery to see if those who had low brain oxygen were mo…