CHRONIC KIDNEY DISEASES

This study looks at how well the HPV9 vaccine (Gardasil 9) works in people who have had a kidney transplant. Researchers will measure antibody levels in 30 transplant recipients over 24 months and compare them to published data from healthy individuals. The goal is to see if the …

This study looks at whether taking cinnamon supplements for three months can lower inflammation and improve gut health in people with chronic kidney disease. Thirty patients will take either cinnamon capsules or a placebo. Researchers will measure markers of inflammation and oxid…

This study explores whether eating alkalizing fruits and vegetables, delivered to your home, can help manage metabolic acidosis in people with chronic kidney disease. The usual treatment, sodium bicarbonate, often causes side effects and doesn't always work. The trial will see if…

This study looks at whether eating Brazil nuts can lower inflammation and oxidative stress in people with chronic kidney disease. Researchers will measure changes in blood and gut bacteria in 50 patients. The goal is to see if this simple food can help manage the disease better.

This study looks at whether a natural substance called fisetin can help people with advanced chronic kidney disease. Researchers will measure changes in inflammation, stem cell health, and physical frailty after 14 days of treatment. The study involves 30 adults aged 40-80 with m…

This study looks at whether a combination of nurse health coaching, doctor training, and subsidies for a kidney-protecting drug can help slow the worsening of chronic kidney disease. About 724 adults with moderate-to-severe kidney disease in Singapore will be randomly assigned to…

This study tests a procedure called renal denervation, which uses a device to calm overactive nerves in the kidneys that can raise blood pressure. About 1,900 adults with uncontrolled high blood pressure will receive the treatment and be followed for years to see if it safely and…

This early-phase study tests whether the drug belumosudil can help people who receive a kidney transplant along with a stem cell transplant from the same donor. The goal is to see if it is safe and allows patients to stop taking most anti-rejection medicines over time. Sixteen ad…

This study tests a new ultrasound technique that uses tiny bubbles to create detailed images of blood vessels in the kidney. Researchers hope this can help diagnose chronic kidney disease without an invasive biopsy. The study involves 186 healthy volunteers and kidney disease pat…

This study tests a virtual reality platform designed for people on hemodialysis. The platform includes games to encourage exercise, plus nutritional advice and psychological support. Researchers hope it will improve patients' walking ability, quality of life, and overall well-bei…

This study is testing whether a detailed MRI scan can provide better information about chronic kidney disease (CKD) than standard tests. Researchers will scan 486 adults with CKD and track their health over time to see if the MRI can predict which patients will get worse. The goa…

This observational study will collect genetic and health information from 120,000 people with chronic conditions like pancreatitis, inflammatory bowel disease, diabetes, and arthritis. Researchers will analyze how genes, lifestyle, and other factors affect disease progression and…

This study planned to use a machine learning algorithm to estimate blood potassium levels from a single-lead ECG in hospitalized patients. It was designed as a retrospective analysis of existing data from a home hospital program. However, the study was withdrawn before enrolling …

This study planned to use machine learning to predict how long patients would stay in a home hospital program. Researchers would have analyzed past patient data to train a computer algorithm. However, the study was withdrawn before any participants were enrolled, so no results ar…

This study is creating a registry of 5,000 adults with chronic kidney disease (CKD) to track their health over time. Researchers will collect information on diagnosis, treatment, and outcomes like kidney function decline, heart problems, and death. The goal is to understand curre…

This pilot study tests a program that screens older dialysis patients for common age-related problems like falls, memory trouble, and medication issues. A geriatrics team then gives personalized recommendations to the dialysis clinic. The goal is to see if this approach is practi…

This study looked at over 16,000 people in Spain aged 45-70 who had risk factors like high blood pressure or smoking but no known heart disease. Researchers used ultrasound and urine tests to find hidden artery and kidney problems. The goal is to learn what factors lead to these …

This study aimed to see how changing the amount of fluid, the time it stays in the belly, and the sugar level in the dialysis solution affects how much water is removed during automated peritoneal dialysis. It was designed for adults with chronic kidney disease who had been on di…

This study uses advanced MRI techniques to measure changes in heart muscle tissue in 8,000 adults with heart failure, heart muscle disease, inflammation, coronary artery disease, or chronic kidney disease. The goal is to see if these measurements can help doctors better diagnose …

This study follows nearly 800 people with chronic kidney disease who previously took part in a program to help them get a transplant. Researchers want to see if the support they received still helps them talk to doctors, find a living donor, or complete the transplant evaluation.…

This study looks at muscle and fat in 80 people with chronic kidney disease (CKD) and compares them to healthy volunteers. The goal is to understand when and how muscle loss happens in CKD, so future treatments can be developed to improve health and quality of life. Participants …

This study tests a decision aid that gives people with chronic kidney disease clear information about pregnancy and contraception. About 70 participants will use the tool and then answer a survey to see if it helps them feel more prepared to make reproductive health decisions. Th…

This study follows 600 people with and without chronic kidney disease (CKD) for up to four years to compare how often memory loss, confusion, and daily activity problems occur. Researchers will also look for risk factors that make thinking and memory worse in CKD patients. Partic…

This study looks at how two drugs, Sacubitril/Valsartan (Entresto) and MANP, affect people with a type of heart failure called HFpEF, which also involves chronic kidney disease or shortness of breath during exercise. Researchers will measure changes in body chemicals and kidney f…

This study collects information from about 1000 critically ill infants who need a special type of dialysis (blood cleaning) using a new machine called CARPEDIEM. The goal is to learn why doctors start this treatment, how to best use it, and what happens to the babies afterward. T…

This study explores whether low levels of pyrophosphate, a natural substance that prevents hardening, can predict artery calcification in people with moderate chronic kidney disease. Researchers will measure pyrophosphate in 242 participants and track changes in artery calcificat…