New drug combo tested for stiff heart and kidney troubles
NCT ID NCT05279742
First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 23 times
Summary
This study looks at how two drugs, Sacubitril/Valsartan (Entresto) and MANP, affect people with a type of heart failure where the heart pumps well but is stiff (HFpEF), along with chronic kidney disease. Researchers will measure changes in blood and urine markers after giving the drugs or a placebo. The goal is to understand how these drugs work in different patient groups, not to cure or treat symptoms directly.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
Conditions
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