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Can cinnamon tame kidney disease inflammation?

NCT ID NCT06286735

Disease control Sponsor: Universidade Federal Fluminense Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking cinnamon supplements for three months can lower inflammation and improve gut health in people with chronic kidney disease. Thirty patients will take either cinnamon capsules or a placebo. Researchers will measure markers of inflammation and oxidative stress to see if cinnamon helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cinnamon (cinnamomum) supplement
What this could lead to
If it works, this could point toward a simple, natural way to reduce inflammation and improve gut health in people with chronic kidney disease.
What could go wrong
This is a very small, early-stage trial with only 30 participants. The results may not apply to all kidney patients, and the supplement might not show a clear benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients with CKD undergoing conservative treatment stages G3a-G4 * patient in stage 5 (GFR \< 15 mL/min), undergoing hemodialysis for more than 6 months and having an arteriovenous fistula (AVF) as vascular access. Exclusion Criteria: * pregnant, lactating, smoker patients * patients using antibiotics in the last 3 months, antioxidant supplements and habitual cinnamon intake * patients with autoimmune and infectious diseases, cancer, liver disease and AIDS, illiterate people and people with disabilities (visual, hearing) * patients who are allergic or intolerant to the components of the capsules.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney diseases

Contacts and locations

Locations

  • Fluminense Federal University

    Rio de Janeiro, Rio de Janeiro, 22260050, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.