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New MRI scan could revolutionize kidney disease monitoring

NCT ID NCT04238299

Knowledge-focused Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a detailed MRI scan can provide better information about chronic kidney disease (CKD) than standard tests. Researchers will scan 486 adults with CKD and track their health over time to see if the MRI can predict which patients will get worse. The goal is to improve monitoring and guide treatment without needing a kidney biopsy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this MRI method could help doctors predict kidney disease progression more accurately and choose better treatments without needing a biopsy.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve health. The MRI technique may not prove more useful than current tests.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

486 people

The number who actually took part.

Started

Jun 2021

Expected to finish

Feb 2033

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Chronic kidney disease

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Age 18-75 years * CKD category G3-4 or CKD category G1-2 with overt albuminuria (urine ACR\>30mg/mmol) * Capable of giving informed consent Exclusion Criteria * Autosomal dominant polycystic kidney disease (ADPKD) * Glomerulonephritis (GN) actively receiving immunosuppression, or within the preceding 90 days. * Multiple myeloma (MM) * Acute Kidney Injury (AKI) within the preceding 90 days * Solid organ transplant * Known single kidney * Contraindications to MRI (e.g. permanent pacemaker, metallic foreign bodies, claustrophobia etc.)

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney diseases

Contacts and locations

Locations

  • Royal Derby Hospital

    Derby, Derbyshire, DE22 3NE, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.