CHRONIC KIDNEY DISEASES

This study tests whether sending tailored alerts to doctors can increase prescriptions of recommended medications for chronic kidney disease (CKD). About 1,000 adults with CKD will be included, and researchers will track if more patients receive guideline-directed therapy within …

This study looks at whether oral semaglutide, a drug already used for diabetes, can slow down kidney disease in people who also have fatty liver disease. Researchers will follow 90 adults for two years, comparing standard care plus semaglutide to standard care alone. The goal is …

This study tests a new drug called QRX3 in 3000 people with chronic kidney disease (CKD). The goal is to see if QRX3 can slow the loss of kidney function and reduce protein in the urine. Participants must have declining kidney function but not too rapid. The drug aims to improve …

This study looks at whether empagliflozin, a diabetes medicine, can reduce protein leakage in urine for people with type 2 diabetes and severe chronic kidney disease (eGFR between 10 and 20). About 34 adults will take either the drug or a placebo for 6 weeks each. The goal is to …

This study will give a single dose of a radioactive-labeled drug called HRS-1780 to 6 healthy men. Researchers will measure how the drug is absorbed, broken down, and removed in urine and stool. The goal is to understand the drug's path through the body, not to treat any disease.…

This study will use advanced MRI scans to learn more about chronic kidney disease, how transplanted kidneys are doing, and how kidney problems may affect the brain. Researchers will scan the kidneys and brains of 180 people, including healthy volunteers and those with kidney dise…

This observational study looks at how gum disease (periodontitis) and chronic kidney disease may be connected through the 'oral-renal axis.' Researchers will study mouth and gut bacteria in 80 adults aged 18 to 75 to see if these microbes play a role. The goal is to better unders…