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Can starting multiple kidney drugs at once slow Diabetes-Related kidney damage?

NCT ID NCT07547878

First seen Apr 23, 2026 · Last updated Jun 22, 2026 · Updated 13 times

Summary

This pilot study tests whether starting four approved kidney disease medicines quickly (over about 8 weeks) is safe and effective for people with type 2 diabetes and chronic kidney disease. Researchers will compare this rapid approach to usual care, where medicines are started one at a time. The study involves 64 participants and will track kidney function, protein in urine, and how many people can stay on all four medicines for 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor Scott and White Medical Center- Temple

    Temple, Texas, 76508, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Finerenone, Semaglutide, and ACE inhibitors (Benazepril, Captopril, Enalapril, Fosinopril, Lisinopril, Moexipril, Perindopril, Quinapril, Ramipril, Trandolapril)

What this could lead to

If this approach works, it could show that starting multiple kidney-protecting medicines at once is safe and helps slow kidney damage in people with diabetes.

What could go wrong

This is a small pilot study with only 64 people, so results may not apply to everyone. Starting several medicines quickly could increase side effects like high potassium or low blood pressure.

Conditions

The condition(s) this trial relates to.

Albuminuria chronic kidney disease chronic renal failure syndrome Hyperkalemia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.