CHILDREN

This study tested the safety of an extended-release clotting factor injection called BAY94-9027 (Jivi) in children aged 7-12 with severe hemophilia A. The treatment is designed to last longer in the body, potentially requiring fewer injections to prevent and control bleeding epis…

This study tested whether a special education program could help children and teens better understand and manage their type 1 diabetes. Researchers enrolled 68 young patients from a hospital in France to participate in the program. The goal was to see if the education improved th…

This study looked at whether a narrowed urethra opening (meatal stenosis) is linked to bedwetting in boys aged 7-12. Researchers followed 400 boys with bedwetting to see if they had this narrowing. They found that surgery to widen the opening helped many children stop wetting the…

This study tested a program called AWARE to help families and doctors review psychiatric medications that children are taking, especially those prescribed 'off-label' or in combinations of three or more drugs. The goal was to see if a shared decision-making process, using a simpl…

This study tested whether using a low-dose atropine eye drop together with a special soft contact lens works better than the eye drop alone to slow down the worsening of severe nearsightedness in children. It involved 120 Chinese children aged 6-12 with very poor distance vision.…

This study tested a new smartphone app designed to help identify speech delays in children. Researchers compared the app's AI-based assessment to the standard evaluations done by speech-language pathologists. The goal was to see if the app could be a useful and accurate tool for …

This study tested whether a special forehead sensor could accurately measure a child's deep body temperature during and after surgery. It involved 70 children aged from newborns to 16 years old. The goal was to see if this non-invasive method could help doctors better monitor and…

This study tested whether a family-centered program led by community health workers could help prevent obesity in young children. The program involved home visits, text messaging, and coaching on healthy eating and activity for 300 families with children aged 2-6 who were overwei…

This study tested whether visual or sensory distraction tools could help reduce anxiety and pain in young children during dental injections. Researchers compared 100 children aged 4-6 who received either visual distraction, sensory distraction, or no distraction during their dent…

This study compared two ways to give anesthesia to children having hernia repair surgery. Researchers tested whether anesthesia given through an IV drip or through inhaled gas led to more stable vital signs during surgery and a smoother, faster recovery afterward. The goal was to…

This study tested whether adding a gentle, needle-free laser treatment to standard anti-nausea medicine could better prevent vomiting and nausea in children and young adults (ages 2-20) undergoing chemotherapy. The laser was aimed at specific acupuncture points on the body. Resea…

This study compared two methods of pain relief for children aged 1-7 having hernia repair surgery. Researchers tested whether a newer ultrasound-guided numbing technique works as well as a standard method for managing pain after surgery. The trial involved 50 children to see whic…

This study compared two different methods of blocking pain for children aged 2-7 having lower abdominal surgery. Doctors tested whether an 'erector spinae block' or a 'caudal block' was better at managing pain during and after the operation. They measured children's pain levels, …

This study tested two simple distraction methods to help children aged 7-12 cope with the pain, fear, and anxiety of getting a blood draw. Researchers compared having kids blow bubbles with a material-free technique using conversation and positive reinforcement. The goal was to s…

This study tested if a specific injection technique in the hip area could make shots less painful for children. Researchers compared 90 kids aged 6-12, giving some the new technique and others the standard method. They found the new technique led to significantly less pain and a …

This study tested two simple, drug-free methods to reduce pain and fear in young children getting shots in the emergency room. Researchers compared a special tapping technique and a plastic device called a ShotBlocker against each other to see which worked better. The trial invol…

This study tested whether applying a numbing cream called Emla before a routine baby vaccine helps reduce pain. It involved 72 healthy three-month-old infants getting their first pneumococcal shot. Researchers compared pain scores, crying time, and heart rate between babies who g…

This study tested whether melatonin patches placed on the skin could safely reduce anxiety in children during dental visits. It involved 52 children aged 5-7 who needed dental work. Researchers compared children who received real melatonin patches to those who received placebo st…

This study tested whether simple distractions like playing digital games or watching cartoons could help children feel less pain, fear, and anxiety while getting stitches in the emergency room. Researchers worked with 90 children aged 5 to 10, dividing them into groups that eithe…

This study tested if watching a special cartoon through virtual reality (VR) glasses could help children feel less anxious, scared, and in pain before and after a heart catheterization. Researchers worked with 42 children aged 5 to 10 who were scheduled for the procedure. They co…

This study tested two new devices designed to measure leg muscle strength and electrical activity in children with cerebral palsy. Researchers worked with 20 children to see if these tools give consistent results and are practical for doctors and therapists to use in clinics. The…

This completed study aimed to better understand how the brain works in people with autism spectrum disorders (ASD). Researchers studied 678 participants, including people with ASD, healthy volunteers, and their parents, using interviews, thinking tests, brain scans (MRI/MEG), and…

This study aimed to create and test a new questionnaire to measure how much children with asthma know about managing their condition. Researchers worked with 196 children aged 8-12 who have asthma. The goal was to develop a reliable tool that can help identify what information ki…

This study collected and analyzed hospital records for 761 children who had pancreatic surgery in Germany between 2010 and 2023. Researchers wanted to understand how often serious complications or death occurred after these operations in children, since this information was previ…

This study aimed to understand how often doctors have trouble placing a common breathing device in children's airways during surgery and to identify what factors make placement difficult. It observed 3,750 children aged 1 to 12 who were having planned surgery. The goal was to gat…

This study looked at whether a parent's anxiety before their young child's groin-area surgery affects the child's own anxiety before the operation and their pain levels afterward. Researchers measured anxiety and pain in 81 children aged 2-6 and their parents. The goal was to und…

This study aimed to understand and compare how doctors across France treat children with supraventricular tachycardia (SVT), a common type of fast heart rhythm. It observed 1,400 children under 18 to see which medications and procedures were used, how well they worked, and what s…

This study looked at how different types of play affect children's physical fitness and social skills. Researchers compared traditional, rule-based games with unstructured free play in 104 primary school children aged 5-9. The goal was to understand which type of activity might b…