CARDIOVASCULAR RISK FACTOR
Clinical trials for CARDIOVASCULAR RISK FACTOR explained in plain language.
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Southern-Style mediterranean diet takes on weight watchers in weight loss showdown
Disease control CompletedThis study tested a new weight loss program called Med-South, which adapts the Mediterranean diet for Southern tastes, against the popular WW (Weight Watchers) program. Over 360 adults with obesity took part for 2 years. The goal was to see which approach leads to more weight los…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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HIV drug switch may protect hearts: small study hints at benefit
Disease control CompletedThis early-phase study tested whether switching HIV medications to doravirine (with emtricitabine/tenofovir alafenamide) could improve cholesterol and reduce early signs of heart disease in 26 people with well-controlled HIV. Participants had stable HIV and high cholesterol. The …
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: EARLY_PHASE1 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
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Step up to health: online program aims to prevent heart disease
Prevention CompletedThis study tested a year-long online program to help adults aged 40-70 who are at risk for heart disease become more active. Participants received a fitness tracker, online coaching, and educational sessions. The goal was to see if this approach could increase daily steps and hel…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated May 22, 2026 13:55 UTC
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Stretching may lower blood pressure in pregnant women with obesity
Symptom relief CompletedThis study looked at whether a stretching routine could reduce heart health risks in pregnant women with obesity. 224 women from 27 to 37 weeks of pregnancy either did stretching exercises or followed standard moderate activity guidelines. The main goal was to see if stretching i…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated May 26, 2026 02:57 UTC
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Ketone drink shows promise for heart and brain health in small study
Symptom relief CompletedThis study tested whether drinking a ketone supplement for two weeks could improve blood vessel health and thinking skills in adults aged 50-75. Eleven participants each took the ketone drink and a placebo for two weeks, with a break in between. Researchers measured artery stiffn…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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Choline pills may impact blood vessel function, study finds
Knowledge-focused CompletedThis study looked at whether taking choline supplements for a short time changes how well blood vessels work in healthy adults. Twenty participants took choline or a placebo for five days each, with a break in between. Researchers measured blood flow in the arm and artery stiffne…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:56 UTC
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Exercise intensity may alter hunger hormone in obesity and prediabetes
Knowledge-focused CompletedThis study looked at how different exercise intensities change levels of ghrelin, a hormone that controls hunger, in 40 adults with obesity and prediabetes. Researchers measured ghrelin in the blood and checked appetite, insulin sensitivity, and blood vessel function. The goal wa…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated May 26, 2026 02:54 UTC
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Choline pill study probes Gut-Heart connection
Knowledge-focused CompletedThis study looked at how a single dose of choline, a nutrient found in foods like eggs and meat, affects blood vessel function in 29 healthy adults. Researchers measured artery flexibility and blood flow after participants took choline or a placebo. The goal was to understand if …
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:53 UTC
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Stand up for your health: simple swap lowers blood sugar in At-Risk group
Knowledge-focused CompletedThis study looked at whether replacing sitting time with standing and walking can improve daily blood sugar levels in South Asian adults who are overweight or obese. Eighteen participants changed their daily routines to sit less and move more. The results showed that this simple …
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Bedfordshire • Aim: Knowledge-focused
Last updated May 26, 2026 02:48 UTC
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Salty meal study reveals hidden heart risks for black adults
Knowledge-focused CompletedThis study looked at how a single high-salt meal affects blood pressure and blood vessel function in healthy Black and white adults aged 19-40. Researchers measured changes in blood flow and stiffness before and after the meal to see if Black individuals respond differently, whic…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated May 26, 2026 02:46 UTC
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Sleep therapy may protect hearts of PTSD patients
Knowledge-focused CompletedThis study looked at whether treating insomnia can lower the risk of heart disease in people with PTSD. Researchers measured blood pressure, blood vessel function, and other heart risk factors in 140 adults aged 40-59. The goal was to see if improving sleep could also improve hea…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 26, 2026 02:44 UTC
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Teen diet and lifestyle linked to heart risk years later
Knowledge-focused CompletedThis study followed 72 young adults who were part of a larger teen health study 10 years earlier. Researchers looked at their current heart disease risk using a special score and compared it to their teenage diet and lifestyle. The goal was to find new risk factors and identify g…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 26, 2026 02:43 UTC
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Study probes hidden links between job stress and obesity in poor communities
Knowledge-focused CompletedThis study looked at how stress, behavior, and social factors affect weight loss and heart health in people from disadvantaged backgrounds. Researchers tracked 15 adults with overweight or obesity to understand what helps or hinders weight management. The goal was to gather infor…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Eggs vs. pills: which choline source spikes heart risk marker?
Knowledge-focused CompletedThis study looked at how choline from eggs compares to choline from supplements in affecting TMAO, a compound in the blood linked to higher heart disease risk. About 86 adults participated, and researchers measured TMAO levels and platelet function over 28 days. The goal was to s…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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OJ vs. soda: which is worse for your heart?
Knowledge-focused CompletedThis study looked at how drinking orange juice compared to a sugary drink affects risk factors for heart disease and type 2 diabetes. Fifty-six adults drank either orange juice or a sugar-sweetened beverage for four weeks. Researchers measured changes in cholesterol, blood sugar …
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Tiny plaques, big clues: study probes hidden heart risks
Knowledge-focused CompletedThis study looked at 90 people with low or medium heart risk to see if tiny, non-blocking plaques in the heart arteries affect how blood clots and how blood vessels work. Participants had a special CT scan to find these small plaques, and their blood was tested for clotting activ…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Sponsor: University of Sao Paulo • Aim: Knowledge-focused
Last updated May 18, 2026 12:11 UTC
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Could your workout routine protect your gums?
Knowledge-focused CompletedThis study looked at 61 adults to see if physical fitness, diet, and body measurements like weight and waist size are linked to gum disease. Researchers reviewed dental records and questionnaires from a previous study. The goal was to understand how lifestyle factors might affect…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Sponsor: Universidad Rey Juan Carlos • Aim: Knowledge-focused
Last updated May 18, 2026 12:11 UTC
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Stand up, walk around: simple breaks may cut diabetes risk in south asians
Knowledge-focused CompletedThis study looked at whether taking short, regular walks during long periods of sitting can help lower blood sugar and cholesterol after meals—key risk factors for Type 2 diabetes and heart disease. Researchers compared normal-weight and overweight/obese South Asian adults, a gro…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Bedfordshire • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC
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Salt sensitivity secrets revealed in small study
Knowledge-focused CompletedThis study looked at how salt in the diet affects blood pressure in Black adults. 19 participants ate both high-salt and low-salt diets to see how their bodies handled salt. The goal was to understand the link between salt and blood pressure, not to test a treatment.
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC