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Salty meal study reveals racial differences in blood pressure response

NCT ID NCT04244604

Knowledge-focused Sponsor: Indiana University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a single high-salt meal affects blood pressure and blood vessel function in healthy adults aged 19-40. Researchers compared Black and white participants to see if there are racial differences in how the body handles salt. The goal is to understand why Black individuals are more prone to salt-related high blood pressure and heart problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

71 people

The number who actually took part.

Started

May 2021

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Are between the ages of 19-40. 2. Have blood pressure no higher than 140/90 mmHg. 3. Have a BMI below 35 Kg/m2 (otherwise healthy) 4. Free from metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD, severe asthma, or cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular). 5. Do not have any precluding medical issues that prevent participants from exercising (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis) or giving blood (e.g., blood thinners). 6. Are not currently smoking, using smokeless tobacco, nor smoked within the past 12 months. Exclusion Criteria: 1. High blood pressure - greater than 140/90 mmHg 2. Obesity (BMI \> 30 kg/m2) 3. History of metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD, severe asthma, or cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular) 4. Medical issues that prevent safe exercise (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis) 5. Medical issues that prevent giving blood (e.g., blood thinners) 6. Currently smoking, using smokeless tobacco, or vaping (within past 12 monrths) 7. Current pregnancy

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Conditions

The condition(s) this trial relates to.

Hypernatremia hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood pressure Cardiovascular risk factor Racial disparities Sodium excess

Contacts and locations

Locations

  • Auburn University

    Auburn, Alabama, 36849, United States

  • Indiana University School of Public Health

    Bloomington, Indiana, 47405, United States

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