Salt sensitivity secrets revealed in small study
NCT ID NCT03696433
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how salt affects blood pressure in Black adults. Researchers wanted to see if changes in blood pressure from eating more or less salt were linked to signs seen on medical scans. 19 people took part, and the goal was to learn more, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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19 people
The number who actually took part.
- Started
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Feb 2019
- Finished
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Nov 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Identification as black race * Age between 18 and 55 years * Body mass index between 25 and \<35 kg/m2 * Normotensive or pre-hypertensive * Willing to adhere to study diets * Able to provide informed consent and communicate with study personnel Exclusion Criteria: * Prevalent cardiovascular disease or use of medications for cardiovascular disease * Current or prior history of hypertension or use of blood pressure lowering medications * Current or prior history of diabetes mellitus or use of anti-diabetic medications * Prevalent renal disease (eGFR \< 60 ml/min/1.73m2), abnormal serum sodium or potassium * Current or prior smoker * Current pregnancy, or use of hormone replacement therapy or oral contraceptive * Current steroid use * Contraindications to MRI * Active infection or open wounds on the top of the feet or hands
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, 37212, United States
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