Ketone drink shows promise for heart and brain health in small study
NCT ID NCT04236388
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether drinking a ketone supplement three times a day for two weeks could improve blood vessel health and thinking skills in adults aged 50-75. Eleven participants each tried the ketone drink and a placebo, with a two-week break in between. The goal was to see if the drink could lower blood pressure and improve artery function and attention.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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11 people
The number who actually took part.
- Started
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Oct 2020
- Finished
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May 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ability to provide informed consent * 50-75 years of age * Systolic blood pressure \<160 mmHg * Diastolic blood pressure \<100 mmHg * Sedentary to recreationally active * Body Mass Index \<35 kg/m\^2 * Postmenopausal women must be \>1 year since last menses Exclusion Criteria: * Current smoker * Pregnant or planning to become pregnant * Dyslipidemia (Total cholesterol \>240 mg/dL, LDL \>160 mg/dL) * Chronic clinical disease (e.g., inflammatory bowel disease/irritable bowel syndrome, unstable coronary heart disease, stroke, heart failure, diabetes, neurological disorders) * Following an extreme dietary pattern or planning to change to one (e.g., low carbohydrate, carnivore) * Not weight stable in the prior 3 months (\>2 kg weight change)
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Virginia Polytechnic and State University
Blacksburg, Virginia, 24061, United States
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