ATRIAL FIBRILLATION (AF)

This study tests a new device called the Amulet 2, which is placed in the heart to seal off a small pouch where blood clots often form in people with atrial fibrillation (AF). The goal is to lower the risk of stroke without needing lifelong blood-thinning medication. About 458 ad…

This study looks at 300 adults who had a heart procedure called ablation for atrial fibrillation. It compares two methods of giving the blood thinner heparin: a steady drip versus occasional shots. The goal is to see which method keeps blood clotting time in the ideal range (250-…

This study looks at 300 people having a procedure for atrial fibrillation (an irregular heartbeat). During the procedure, doctors measure the blood pressure inside the heart's left upper chamber. If it is high, it may mean the heart is struggling with unrecognized heart failure. …

This study tests a new device system (TactiFlex SE catheter and Volt generator) that uses pulsed field ablation to treat paroxysmal atrial fibrillation, a type of irregular heartbeat. The goal is to see if the procedure is safe and effective for people whose symptoms haven't impr…

This study compares two ways to perform a heart procedure for atrial fibrillation (AFib), a condition causing irregular heartbeat. One method uses X-ray guidance, while the other avoids X-rays entirely. About 724 adults aged 18-80 with AFib will be randomly assigned to one of the…

This study tests a new drug called abelacimab against the standard blood thinner rivaroxaban in about 1,300 people with atrial fibrillation who are at moderate-to-high risk of stroke. The goal is to see if abelacimab causes fewer serious or nuisance bleeding events while still pr…

This study tests whether specially trained pharmacists can help people with atrial fibrillation take their blood thinner medications more consistently. About 400 adults with AF who are starting a blood thinner will either get usual care or extra one-on-one education from a pharma…

This study looks at whether people with recent-onset atrial fibrillation (AFib) who get a heart ablation procedure right from the emergency room have fewer heart rhythm problems over the next year compared to those who get standard treatment. About 350 adults with AFib that start…

This study looks at whether a small, single-lead ECG device used at home can help find people with undiagnosed atrial fibrillation (AF), a common heart rhythm problem. Researchers will use an AI tool to predict who might have AF and then check them with the handheld device. About…

This study aims to see if a newer MRI contrast agent (Gadopiclenol) can produce clearer images of heart damage in people with atrial fibrillation compared to standard contrast agents. About 50 adults with atrial fibrillation will receive a research MRI scan. The goal is to improv…

This study tests whether smartphones can accurately detect atrial fibrillation (AF), a common heart rhythm problem, using built-in sensors like microphones and cameras. About 209 adults with and without AF will have their heart sounds, electrical signals, and blood flow recorded …

This study looks at whether using a special blood pressure monitor at home can find atrial fibrillation (an irregular heartbeat) sooner in older adults with high blood pressure. About 1,900 people aged 60 and older will take daily readings and answer app surveys for up to 18 mont…

This study tests a safe, non-invasive method to improve thinking and memory in people over 60 with atrial fibrillation (AF). The approach uses low-frequency electrical stimulation on the ear to activate the vagus nerve, which may enhance brain function. Sixty participants will re…

This study tests two methods to close the blood vessel after a common heart procedure for atrial fibrillation. One method uses a special disc (StatSeal) and the other uses a stitch (figure-of-eight). The goal is to see which helps patients get up and walk sooner. About 160 adults…

This study looks at people with atrial fibrillation (an irregular heartbeat) whose first ablation procedure didn't work. It compares two repeat ablation techniques: the standard approach versus adding extra treatment to another part of the heart. The goal is to see which method b…

This study looks at whether a new algorithm can predict if atrial fibrillation (an irregular heartbeat) will return after a procedure called pulmonary vein isolation. Researchers will review records from 300 people who had this procedure, checking their heart's electrical signals…

This study looks at how doctors use the FARAPULSE system to treat atrial fibrillation (an irregular heartbeat) in routine care. Researchers will collect information from about 524 patients to see which steps before, during, and after the procedure work best. The goal is to find t…

This study tests a training program that teaches family doctors how to use focused heart ultrasound. About 500 patients with suspected heart issues will have both a family doctor's ultrasound and a cardiologist's full exam. The goal is to see how well the doctors' results match t…

This study is testing whether monthly heart checks (ECGs) at local health clinics can find undiagnosed atrial fibrillation—a common, often silent heart rhythm problem—in adults aged 65 and older. Over 1,000 participants in Ordu, Turkey will get a quick, painless ECG once a month …

This study looks at a new method to analyze electrical signals in the heart to better locate the abnormal tissue causing atrial fibrillation (AFib). Researchers will review data from 336 patients who had a standard AFib ablation procedure. They will compare maps from patients who…

This study observes people with atrial fibrillation who are scheduled for a standard heart procedure called PFA (pulsed field ablation). The goal is to see if the procedure sometimes injures the phrenic nerve, which controls the diaphragm muscle used for breathing. Participants g…

This study aims to create a digital tool that uses information already collected during hospital stays—like blood tests and blood pressure—to identify patients who may have undiagnosed chronic conditions such as diabetes or heart disease. By analyzing millions of patient records,…

This study compares six different 7-day ECG patches in adults aged 65 and older who need heart rhythm monitoring. The goal is to see which patches provide the most usable and high-quality recordings over a week. Results will help doctors choose the best patch for everyday heart m…

This study tests whether a smartwatch (Apple Watch or PulseOn) can detect hidden atrial fibrillation (AF) in 84 stroke patients who already have an implanted heart monitor. Participants wear the watch for 12 weeks, and the watch alerts them if it senses an irregular pulse, allowi…

This study looks at 1,000 adults aged 65 and older with atrial fibrillation who get their care at family health centers in Ordu, Türkiye. Researchers will check if patients are taking the correct dose of their blood thinner and how often they take it as prescribed. No new treatme…

This study watches 40 adults who need a leadless pacemaker (Micra AV) to see if where the device sits inside the heart changes the heart's electrical signals or pumping ability. Researchers will use CT scans and ECGs to measure heart function and valve leakage. The goal is to fin…