ATHEROSCLEROSIS

This study looked at whether the flu vaccine can reduce inflammation in people with stable coronary artery disease. Inflammation plays a key role in heart disease progression. Researchers measured blood markers of inflammation in 47 older adults before and after vaccination. The …

This study looked at how well the ELUVIA drug-coated stent works in real-world patients with blocked arteries in the thigh or knee area. About 291 adults received the stent and were followed for two years. Researchers measured changes in quality of life and walking ability to see…

This study tested a digital quality improvement program to help people with heart disease lower their LDL (bad) cholesterol. Over 1,400 patients in Brazil used a smartphone-based tool to improve cholesterol management. The goal was to see if this approach helps doctors and patien…

This study tested whether colchicine, an anti-inflammatory drug, can reduce inflammation in the arteries of people with diabetes or pre-diabetes who recently had a heart attack or stroke. 115 participants received colchicine or placebo, and researchers used PET scans to measure c…

This study tested a new medicine called olezarsen in about 1,500 adults with very high triglycerides (a type of blood fat) and either heart disease or high risk for it. The goal was to see if olezarsen could lower triglyceride levels more than a placebo over 25 weeks. Participant…

This pilot study tested whether delivering the drug paclitaxel directly to the artery wall during a standard leg artery procedure could help keep the artery from narrowing again. 27 adults with leg pain from blocked arteries took part. The goal was to see if this approach improve…

This study tested whether injecting donor stem cells into the leg muscles of people undergoing major leg amputation could prevent wound complications and reduce the need for further amputations. 81 adults aged 40-90 with severe artery disease received stem cell injections above a…

This study tested whether ticagrelor, a stronger anti-clotting drug, reduces heart muscle damage compared to standard clopidogrel in 180 patients with hardened heart arteries. All patients took aspirin and either ticagrelor or clopidogrel before a procedure that grinds away calci…

This study worked with the Oneida community to create a stroke awareness team that held health events. The goal was to teach people about stroke signs and how to lower risks through lifestyle changes. About 120 high-risk adults took part, and the program tracked things like blood…

This study looked at whether patients who had a heart attack, stroke, or other blood vessel problems were prescribed the right cholesterol-lowering medicine when they left the hospital. The goal was to see how well doctors followed official guidelines. 129 patients were included,…

This study looked at whether vitamin D levels are linked to early signs of artery disease in people on hemodialysis. Researchers measured vitamin D in the blood of 90 adults who had been on dialysis for at least 6 months. They then checked for artery hardening. The goal was to se…

This study looked at whether newer psoriasis medications (IL17 and IL23 inhibitors) can also help reduce early signs of heart disease. Researchers measured artery stiffness in 66 patients with moderate-to-severe psoriasis before and after one year of treatment. The goal was to se…

This study looked at a small molecule called microRNA-210 in 230 people with peripheral artery disease (PAD), a condition that causes leg pain and poor blood flow. Researchers measured the molecule's levels in calf muscle samples and tested how far participants could walk. The go…

This study measured two types of cells in the blood that reflect blood vessel injury and healing. Researchers wanted to see if these cell counts could predict major heart problems like heart attack or death within 6 to 12 months after a stent procedure. The study involved 170 adu…

This study looked at 320 people with atherosclerosis (hardening of the arteries) to see how genetic, biological, and imaging factors relate to the disease getting worse over 10 years. Researchers used ultrasound scans to track changes in the arteries of the legs and neck. The goa…

This study looked at 91 Chinese patients with atrial fibrillation who had a stroke despite taking blood thinners (NOACs). Researchers wanted to understand the causes and how taking medication as prescribed affects outcomes. The goal is to find ways to prevent these strokes and im…

This study looked at how excess belly fat relates to early signs of heart disease in 357 healthy adults aged 35-65. Using MRI and CT scans, researchers measured fat distribution and artery plaque buildup. The goal was to better understand the link between body shape and heart ris…

This study looked at how a high-dose fish oil supplement (E-EPA) affects LDL cholesterol in 68 healthy adults aged 18-65. Participants added the supplement to their normal diet for one month. Researchers measured how easily LDL cholesterol clumps together, which is linked to hear…