ATHEROSCLEROSIS

This study compares two ways to place stents in complex heart blockages: using standard X-ray guidance versus adding an ultrasound probe inside the artery. The goal is to see if ultrasound helps doctors choose better stents and place them more precisely, reducing the chance of fu…

This study compares a comprehensive program of lifestyle changes, cholesterol-lowering drugs, and PET heart scans against standard medical care for people with stable coronary artery disease. About 1,085 adults aged 40 and older with suspected or known heart disease are participa…

This study looked at over 16,600 people in Spain who had risk factors like high blood pressure or smoking, but no known heart disease. Researchers used ultrasound and urine tests to find hidden signs of artery and kidney disease. The goal is to learn what factors predict these hi…

This study aimed to compare two FDA-approved devices used to seal the artery after a heart catheterization procedure. The goal was to see if using both devices together could shorten the time patients need to lie flat and recover. However, the study was withdrawn before enrolling…

This study looks at whether bacteria living in your gut and mouth are connected to the risk of stroke in people with narrowed neck arteries. Researchers will measure certain waste products from these bacteria in the blood and track who later has a stroke or worsening artery block…

This study looks at how high-protein drinks affect certain blood cells (monocytes and platelets) that may play a role in heart disease. Ten healthy adults will drink either a low-protein, high-protein, or leucine-added meal, and researchers will measure cell changes over several …

This study was designed to see if a cholesterol-lowering drug called a PCSK9 inhibitor can also reduce inflammation in the arteries of people with heart disease. Researchers planned to use a special imaging scan to measure inflammation. However, the study was withdrawn before enr…

This study is testing a computer model that predicts whether stents placed in the leg arteries might break or fail over time. Researchers will follow 30 adults with blocked leg arteries who receive a stent, and compare the model's predictions to what actually happens. The goal is…

This study is creating a large collection of heart images (like CT scans and angiograms) from 1,000 people. The goal is to help researchers better understand atherosclerosis, a condition where arteries become clogged. No new treatments are being tested—this is purely about gather…

This long-term study followed over 6,400 adults from different racial and ethnic backgrounds to learn how early signs of heart disease develop and lead to serious events like heart attacks or strokes. Participants were healthy at the start and were monitored for years through exa…

This study follows 2,314 South Asian adults (ages 40-84) in the US to uncover why they have high rates of heart disease and stroke, even without typical risk factors. Researchers measure artery calcium, diabetes, and other markers over time. The goal is to identify unique causes …

This study tests a new way to find unstable plaque in the heart arteries of people who come to the emergency room with chest pain but are not having a heart attack. Researchers will use a calcium score scan and a special PET scan to see which patients have hidden risky plaque. Th…