ATHEROSCLEROSIS

This study compares two cholesterol-lowering approaches in about 1,950 adults with chronic kidney disease and heart or blood vessel disease. One group gets a moderate statin plus ezetimibe, the other a high-dose statin alone. The goal is to see which strategy better prevents majo…

This study tests an experimental drug called YN001 in 456 adults with coronary atherosclerosis (plaque buildup in heart arteries). Participants will receive either YN001 or a placebo by IV, alongside their usual heart medications. The main goal is to see if YN001 reduces non-calc…

This study looks for early signs of artery hardening in people with both type 2 diabetes and chronic kidney disease. Using a safe neck ultrasound, researchers will check how common these hidden changes are and how they relate to kidney function and blood sugar. The goal is to hel…

This study will see if an AI program called CaRi-Heart can help doctors make better treatment decisions for people with heart disease. The AI looks at inflammation in the heart arteries using pictures from a regular CT scan, with no extra cost or radiation. Researchers will compa…

This study will examine 100 adults on hemodialysis to see how traditional heart risk factors (like high blood pressure and diabetes) and dialysis-specific factors (like treatment length) relate to the thickness of the carotid artery wall. The goal is to better understand why hear…

This study looks at 70 children and teens with juvenile lupus to see if they have early signs of heart disease. Researchers will use ultrasound to measure the thickness of the carotid artery wall and compare it to healthy children. The goal is to understand how lupus and its trea…