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New blood thinner may protect heart during artery surgery

NCT ID NCT02505399

First seen Jan 06, 2026 · Last updated Apr 30, 2026 · Updated 16 times

Summary

This study tested whether a newer antiplatelet drug, ticagrelor, is better than the standard clopidogrel at preventing heart muscle damage during a procedure called rotational atherectomy, which clears hardened calcium from heart arteries. About 180 adults with stable heart disease or a recent mild heart attack took part. The main goal was to measure troponin levels, a marker of heart injury, in the first 24 hours after the procedure.

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Contacts and locations

Locations

  • Clinique Pasteur

    Toulouse, Haute-Garonne, 31000, France

  • Fédération de Cardiologie CHU TOULOUSE

    Toulouse, Haute-Garonne, 31059, France

  • Hospices civils de Lyon

    Lyon, 69000, France

  • University Hospital

    Nîmes, 30000, France

Conditions

Explore the condition pages connected to this study.