New blood thinner may shield heart during artery grinding procedure

NCT ID NCT02505399

First seen Jan 06, 2026 · Last updated Jun 12, 2026 · Updated 21 times

Summary

This study compared two blood thinners—ticagrelor and clopidogrel—in 180 patients with hardened heart arteries undergoing a special cleaning procedure called rotational atherectomy. The goal was to see if ticagrelor could better prevent small blood clots and heart muscle damage during the procedure. Participants were stable heart patients already taking aspirin and clopidogrel before the study.

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Contacts and locations

Locations

  • Clinique Pasteur

    Toulouse, Haute-Garonne, 31000, France

  • Fédération de Cardiologie CHU TOULOUSE

    Toulouse, Haute-Garonne, 31059, France

  • Hospices civils de Lyon

    Lyon, 69000, France

  • University Hospital

    Nîmes, 30000, France

Conditions

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