ACUTE RESPIRATORY FAILURE

This study looked at whether using a non-invasive breathing mask (NIV) could help patients who develop breathing problems after abdominal surgery avoid needing a breathing tube. 300 adults who had abdominal surgery and then had rapid, shallow breathing were randomly assigned to g…

This study tested whether a special physiotherapy program, combining breathing exercises and early movement, could reduce the chance of breathing failure in the week after a breathing tube is removed. It included 245 ICU patients at high risk of breathing problems after tube remo…

This study tested whether a high-flow nasal cannula (a device that delivers warm, moist oxygen at high speeds) reduces deaths compared to standard oxygen therapy in 1,504 adults with severe breathing failure. Participants had low oxygen levels and rapid breathing. The goal was to…

This study looked at 16 adults on breathing machines (ventilators) to see if simpler tests could spot lung injury risk as well as the standard method. Researchers compared three different measurement techniques. The goal was to find a safer, easier way to monitor patients and pre…

This study looked at over 2,300 critically ill adults who needed an emergency breathing tube. Doctors wanted to know whether ketamine or etomidate is safer and leads to better survival. The main goal was to see which drug reduces the risk of death within 28 days.

This study examined whether the initial diagnosis given to patients when they enter the ICU can help predict their risk of dying. Researchers reviewed records of over 1,200 adults admitted to a mixed ICU in 2025. They focused on common critical conditions like sepsis, ARDS, and o…

This study tested a new way to predict if patients with acute respiratory failure can safely stop using a breathing machine. Researchers used a non-invasive imaging technique called electrical impedance tomography (EIT) to measure how well the lungs fill with air during a breathi…

This study observed 862 ICU patients to learn how common high carbon dioxide levels (hypercapnia) are in people with acute breathing failure. Researchers tracked patients' breathing patterns and CO2 levels to understand what factors influence outcomes. The goal was to gather bett…

This study tested three different ways to manage pain and sedation in 90 adults on breathing machines in the ICU. The goal was to see if these strategies are practical and how they affect recovery. The results help doctors understand which approach might work best for future pati…

This study compared two sedative drugs, propofol and ketamine, used when placing a breathing tube in 207 critically ill patients with acute respiratory failure. The goal was to see which drug better keeps blood pressure stable after the procedure. Results help doctors choose the …

This study looked at 55 adults with acute respiratory failure to understand their breathing difficulty, how air moves in their lungs, and how their diaphragm works. The goal was to find clues that might predict which patients need a breathing tube. No new treatment was tested; in…

This study involved 500 adults on breathing machines in the ICU. Researchers compared two ways of measuring airway pressure at the end of a breath to see which better predicts lung injury. The goal was to improve how doctors assess risk and adjust ventilator settings for patients…

This study observed over 4,000 ICU patients in China who needed breathing support for acute respiratory failure. Researchers collected data on treatments, outcomes, and costs to better understand the disease burden. The goal was to gather current information, not to test a new tr…

This study tested whether a special program of rehabilitation delivered by phone and video could help people who needed a breathing machine for severe breathing failure. About 1,900 adults took part, and the program focused on recovery in the ICU, on the regular ward, and after g…

This study looked at over 2,400 critically ill patients who needed breathing machines and medications for shock. Researchers compared early feeding through a tube into the stomach (enteral nutrition) versus feeding through a vein (parenteral nutrition) to see which approach reduc…

This study tested a personalized online decision-support tool called TRACH-Support for families and medical teams facing decisions about long-term breathing support, such as a tracheostomy. The tool was reviewed by 105 family members and healthcare providers, who then completed s…