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Major study tests two common sedatives in Life-Threatening emergencies

NCT ID NCT05277896

First seen Sep 30, 2025 · Last updated May 22, 2026 · Updated 30 times

Summary

This study looked at over 2,300 critically ill adults who needed an emergency breathing tube. Doctors wanted to know whether ketamine or etomidate is safer and leads to better survival. The main goal was to see which drug reduces the risk of death within 28 days.

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Contacts and locations

Locations

  • Denver Health Medical Center

    Denver, Colorado, 80204, United States

  • Hennepin County Medical Center

    Minneapolis, Minnesota, 55415, United States

  • UAB Hospital

    Birmingham, Alabama, 35233, United States

  • University of Colorado Denver

    Aurora, Colorado, 80045, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wake Forest Baptist Medical Center

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.