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Gut feeding vs. IV: which saves more lives in the ICU?

NCT ID NCT01802099

Knowledge-focused Sponsor: Centre Hospitalier Departemental Vendee Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This study looked at whether giving nutrition through a tube into the stomach (enteral) or through a vein (parenteral) early on affects survival in very sick patients who need a breathing machine and heart-support medications. Over 2,400 adults in intensive care units were randomly assigned to one of the two feeding methods. The main goal was to see which approach led to fewer deaths by day 28.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

2,410 people

The number who actually took part.

Started

Mar 2013

Finished

Sep 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Invasive mechanical ventilation expected to be required more than 48 hours * Nutrition started within 24 hours after initiation of endotracheal mechanical ventilation * Treatment with vasoactive drug administered via a central venous catheter * Age over 18 years * Signed information Exclusion Criteria: * Abdominal surgery within 1 month before inclusion * History of esophageal, gastric, duodenal or pancreatic surgery * Bleeding from the esophagus, stomach or bowel * enteral nutrition via gastrostomy or jejunostomy * pregnancy * Treatment-limitation decisions * Current inclusion in a trial on comparison between enteral and parenteral nutrition

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Conditions

The condition(s) this trial relates to.

acute respiratory failure Hyperphagia nosocomial infection Shock

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute respiratory failure Shock

Contacts and locations

Locations

  • CH Docteur Schaffner

    Lens, 62307, France

  • CH Louis Pasteur

    Chartres, 28018, France

  • CH Marc Jacquet

    Melun, 77000, France

  • CH de Dieppe

    Dieppe, 76202, France

  • CH de Montauban

    Montauban, 82013, France

  • CH de Saint Malo

    St-Malo, 35400, France

  • CHD Vendée - service de réanimation

    La Roche-sur-Yon, 85000, France

  • CHI André Grégoire

    Montreuil, 93105, France

  • CHU Amiens

    Amiens, 80054, France

  • CHU Besançon-Hôpital Jean Minjoz

    Besançon, 25000, France

  • CHU Dijon

    Dijon, 21079, France

  • CHU Gabriel Montpied, Clermont Ferrand

    Clermont-Ferrand, 63003, France

  • CHU Grenoble

    Grenoble, 38043, France

  • CHU Lille

    Lille, 59000, France

  • CHU Louis Mourier

    Colombes, 92701, France

  • CHU Paris Cochin

    Paris, 75014, France

  • CHU Pellegrin Tripode

    Bordeaux, 33076, France

  • CHU Pointe à Pitre - Abymes

    Point À Pitre, 97110, France

  • CHU Poitiers

    Poitiers, 86021, France

  • CHU Saint Etienne-Hôpital Nord

    Saint-Etienne, 42055, France

  • CHU Saint Louis

    Paris, 75010, France

  • CHU Saint-Antoine

    Paris, 75012, France

  • CHU Tours

    Tours, 37044, France

  • CHU d'Angers

    Angers, 49933, France

  • CHU de Bicêtre

    Le Kremlin-Bicêtre, 94275, France

  • CHU de Lyon- Hôpital de la Croix Rousse

    Lyon, 69004, France

  • CHU de Nantes - Hôtel Dieu

    Nantes, 44093, France

  • CHU de Nantes, Hopital Laennec

    Nantes, 44000, France

  • CHU de Strasbourg - Hôpital de Hautepierre

    Strasbourg, 67098, France

  • CHU de Strasbourg - Nouvel Hôpital Civil

    Strasbourg, 67091, France

  • Centre Hospitalier Jacques Puel

    Rodez, 12000, France

  • Centre Hospitalier de Beauvais

    Beauvais, 60021, France

  • Centre hospitalier d'Annecy

    Annecy, 74374, France

  • Groupe Hospitalier Paris Saint Joseph

    Paris, 75014, France

  • Hospices Civils de Lyon

    Lyon, 69437, France

  • Hôpital Delafontaine

    Saint-Denis, 93200, France

  • Hôpital Emile Muller

    Mulhouse, 68100, France

  • Hôpital Foch

    Suresnes, 92150, France

  • Hôpital Raymond Poincarre

    Garches, 92380, France

  • Hôpital Tenon

    Paris, 75020, France

  • Hôpital de La Source, CHR Orléans

    Orléans, 45067, France

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