Pilot study tests best way to manage sedation for ventilator patients
NCT ID NCT02219659
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested three different ways to manage pain and sedation in 90 adults on breathing machines (mechanical ventilation) for at least 48 hours. The goal was to see which approach was most practical and how it affected time in the ICU. The study did not aim to cure or treat a disease, but to gather knowledge on improving care for patients with acute respiratory failure.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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90 people
The number who actually took part.
- Start date
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Dec 2014
- Finished
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May 2018
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. ≥ 18 years of age 2. Mechanically ventilated with an expected duration of MV ≥ 48 hours 3. ICU team has initiated continuous sedative and/or /analgesic infusions Exclusion criteria: 1. Admission after resuscitation from cardiac arrest 2. Admission with traumatic brain injury or another acute neurologic event (e,g. stroke, uncontrolled seizures). 3. History of severe dementia 4. Admission because of acute alcohol withdrawal or acute drug intoxication 5. Administration of more than 24 hours of continuous sedation 6. Allergy to fentanyl, midazolam, and/or propofol 7. Lack of informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Long Beach Memorial Medical Center
Long Beach, California, 90806, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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