Vascular disorder
MONDO:0005385A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome.
Also known as: disease of vasculature, disease or disorder of vasculature, disorder of vasculature, vascular disorder, vasculature disease, vasculature disease or disorder, vasculopathy
10728 clinical trials for this condition and its sub-types, 141 tagged with Vascular disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Vascular disorder
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Arterial disorder 11 trials · 5,328 incl. sub-types
30 sub-types
- Hypertensive disorder 1,266 trials · 2,144 incl. sub-types Sub-types →
- Coronary artery disorder 1,267 trials · 1,410 incl. sub-types Sub-types →
- Aortic disorder 45 trials · 646 incl. sub-types Sub-types →
- Arteriosclerosis disorder 24 trials · 473 incl. sub-types Sub-types →
- Peripheral arterial disease 317 trials Sub-types →
- Pulmonary embolism 203 trials Sub-types →
- Hypotensive disorder 129 trials · 161 incl. sub-types Sub-types →
- Carotid artery disorder 41 trials · 114 incl. sub-types Sub-types →
- Arterial occlusion 40 trials · 109 incl. sub-types Sub-types →
- Arteritis 5 trials · 104 incl. sub-types Sub-types →
- Large artery stroke 95 trials
- Pediatric arterial ischemic stroke 14 trials
- Pulmonary artery disease 12 trials
- Fibromuscular dysplasia 6 trials Sub-types →
- Carotid web 3 trials
- Sneddon syndrome 2 trials
- Celiac trunk compression syndrome 2 trials
- Cervical artery dissection 2 trials Sub-types →
- Vertebral artery insufficiency 2 trials
- Absence of the pulmonary artery 1 trial
- Anterior spinal artery stroke 1 trial
- Aberrant subclavian artery 0 trials
- Anterior spinal artery syndrome 0 trials
- Basilar artery insufficiency 0 trials
- Fibromuscular dysplasia, multifocal 0 trials
- Pulmonary artery choriocarcinoma 0 trials
- Pulmonary artery leiomyosarcoma 0 trials
- Retinal arterial tortuosity 0 trials
- Splenic artery aneurysm 0 trials
- Subclavian artery aneurysm 0 trials
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Neurovascular disorder 5 trials · 4,209 incl. sub-types
29 sub-types
- Cerebrovascular disorder 108 trials · 3,292 incl. sub-types Sub-types →
- Migraine disorder 393 trials · 414 incl. sub-types Sub-types →
- Retinal vascular disorder 9 trials · 324 incl. sub-types Sub-types →
- Intracranial hypertension 51 trials · 97 incl. sub-types Sub-types →
- Central nervous system vasculitis 3 trials · 55 incl. sub-types Sub-types →
- Trigeminal autonomic cephalalgia 8 trials · 27 incl. sub-types Sub-types →
- Choroid plexus cancer 0 trials · 11 incl. sub-types Sub-types →
- Choroid cancer 0 trials · 10 incl. sub-types Sub-types →
- Hemangioblastoma 9 trials · 10 incl. sub-types Sub-types →
- Lymphatic malformation 5 8 trials
- Choroideremia 6 trials Sub-types →
- Ornithine aminotransferase deficiency 4 trials
- Benign choroid plexus neoplasm 0 trials · 2 incl. sub-types Sub-types →
- Cavernous sinus meningioma 2 trials
- Central nervous system hemangioma 0 trials · 2 incl. sub-types Sub-types →
- Hemangioma of retina 0 trials · 1 incl. sub-types Sub-types →
- Retinal ischemia 1 trial
- Norman-Roberts syndrome 0 trials
- Wyburn-Mason syndrome 0 trials
- Benign neoplasm of choroid 0 trials Sub-types →
- Central nervous system angiosarcoma 0 trials
- Choroidal dystrophy, central areolar 2 0 trials
- Choroidal dystrophy, central areolar, 1 0 trials
- Choroidal sclerosis 0 trials Sub-types →
- Eyelid capillary hemangioma 0 trials
- Malignant jugulotympanic paraganglioma 0 trials
- Microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability 0 trials
- Neoplasm of aortic body 0 trials
- Retinal dystrophies primarily involving Bruch's membrane 0 trials Sub-types →
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Ischemic disease 62 trials · 938 incl. sub-types
6 sub-types
- Myocardial ischemia 222 trials · 503 incl. sub-types Sub-types →
- Brain ischemia 55 trials · 283 incl. sub-types Sub-types →
- Limb ischemia 94 trials
- Ischemic bowel disorder 8 trials · 15 incl. sub-types Sub-types →
- Peripheral ischemia 2 trials
- Retinal ischemia 1 trial
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Peripheral vascular disease 57 trials · 432 incl. sub-types
11 sub-types
- Peripheral arterial disease 317 trials Sub-types →
- Telangiectasis 13 trials · 45 incl. sub-types Sub-types →
- Intermittent vascular claudication 33 trials
- Raynaud disease 10 trials
- Erythromelalgia 3 trials · 10 incl. sub-types Sub-types →
- May-Thurner syndrome 8 trials
- Diabetic peripheral angiopathy 5 trials
- Mesenteric vascular occlusion 5 trials
- Priapism 4 trials
- Thromboangiitis obliterans 4 trials
- Livedo reticularis 3 trials
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Ocular vascular disorder 0 trials · 349 incl. sub-types
3 sub-types
- Retinal vascular disorder 9 trials · 324 incl. sub-types Sub-types →
- Optic choroid disorder 6 trials · 26 incl. sub-types Sub-types →
- Conjunctival vascular disorder 0 trials
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Vein disorder 15 trials · 324 incl. sub-types
13 sub-types
- Varicose disease 40 trials · 178 incl. sub-types Sub-types →
- Venous insufficiency 50 trials · 98 incl. sub-types Sub-types →
- Phlebitis 13 trials · 21 incl. sub-types Sub-types →
- Portal vein thrombosis 18 trials
- Central retinal vein occlusion 6 trials · 15 incl. sub-types Sub-types →
- Occlusion of tributary of retinal vein 6 trials
- Cavernous sinus meningioma 2 trials
- Vein of Galen aneurysm 2 trials
- Isolated mesenteric vein thrombosis 0 trials
- Isolated splenic vein thrombosis 0 trials
- Malignant jugulotympanic paraganglioma 0 trials
- Pulmonary vein leiomyosarcoma 0 trials
- Superior vena cava angiosarcoma 0 trials Sub-types →
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Vasculitis 63 trials · 286 incl. sub-types
18 sub-types
- Necrotizing vasculitis 0 trials · 143 incl. sub-types Sub-types →
- Arteritis 5 trials · 104 incl. sub-types Sub-types →
- Central nervous system vasculitis 3 trials · 55 incl. sub-types Sub-types →
- Phlebitis 13 trials · 21 incl. sub-types Sub-types →
- Immune complex mediated vasculitis 0 trials · 18 incl. sub-types Sub-types →
- Hypersensitivity vasculitis 0 trials · 16 incl. sub-types Sub-types →
- Kawasaki disease 15 trials
- Cutaneous vasculitis 4 trials · 5 incl. sub-types Sub-types →
- Deficiency of adenosine deaminase 2 3 trials
- Retinal vasculitis 2 trials
- Aortitis 1 trial
- Choroiditis 0 trials · 1 incl. sub-types Sub-types →
- Livedoid vasculopathy 1 trial
- Secondary vasculitis 0 trials · 1 incl. sub-types Sub-types →
- Shwartzman phenomenon 0 trials
- Autoimmune vasculitis 0 trials Sub-types →
- Lymphangitis 0 trials
- Vasculitis, lymphocytic, nodular 0 trials
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Blood vessel neoplasm 0 trials · 254 incl. sub-types
5 sub-types
- Vascular cancer 1 trial · 150 incl. sub-types Sub-types →
- Benign blood vessel neoplasm 0 trials · 103 incl. sub-types Sub-types →
- Hemangioendothelioma 3 trials · 20 incl. sub-types Sub-types →
- Cavernous sinus meningioma 2 trials
- Neoplasm of aortic body 0 trials
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Vascular insufficiency disorder 1 trial · 244 incl. sub-types
9 sub-types
- Venous insufficiency 50 trials · 98 incl. sub-types Sub-types →
- Tricuspid valve insufficiency 83 trials
- Aortic valve insufficiency 56 trials Sub-types →
- Vertebrobasilar insufficiency 7 trials
- Chronic intestinal vascular insufficiency 4 trials
- Vertebral artery insufficiency 2 trials
- Basilar artery insufficiency 0 trials
- Congenital mitral valve insufficiency 0 trials
- Splenic infarction 0 trials
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Venous thromboembolism 242 trials
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Thrombotic disease 178 trials · 224 incl. sub-types
8 sub-types
- Portal vein thrombosis 18 trials
- Coronary thrombosis 14 trials
- Intracranial thrombosis 12 trials · 13 incl. sub-types Sub-types →
- Heparin-induced thrombocytopenia 5 trials
- Acquired purpura fulminans 0 trials
- Isolated mesenteric vein thrombosis 0 trials
- Isolated splenic vein thrombosis 0 trials
- Marantic endocarditis 0 trials
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Vascular occlusion disorder 27 trials · 182 incl. sub-types
2 sub-types
- Arterial occlusion 40 trials · 109 incl. sub-types Sub-types →
- Retinal vascular occlusion 0 trials · 53 incl. sub-types Sub-types →
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Skin vascular disease 5 trials · 135 incl. sub-types
20 sub-types
- Angioedema 19 trials · 66 incl. sub-types Sub-types →
- Behcet disease 38 trials
- Familial multiple nevi flammei 12 trials
- Chilblain lupus 1 trial · 3 incl. sub-types Sub-types →
- Livedo reticularis 3 trials
- Maffucci syndrome 2 trials
- Sneddon syndrome 2 trials
- Blue rubber bleb nevus 2 trials
- Malignant atrophic papulosis 2 trials
- Pityriasis lichenoides 1 trial Sub-types →
- Bockenheimer syndrome 0 trials
- Cobb syndrome 0 trials
- Wyburn-Mason syndrome 0 trials
- Angioma serpiginosum 0 trials Sub-types →
- Atrophic papulosis 0 trials Sub-types →
- Calciphylaxis cutis 0 trials
- Cutaneous collagenous vasculopathy 0 trials
- Cutis marmorata telangiectatica congenita 0 trials
- Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome 0 trials
- Generalized essential telangiectasia 0 trials
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Hepatic vascular disorder 1 trial · 116 incl. sub-types
11 sub-types
- Portal hypertension 90 trials
- Portal vein thrombosis 18 trials
- Hepatic veno-occlusive disease 6 trials Sub-types →
- Fontan-associated liver disease 5 trials
- Portosinusoidal vascular disease 3 trials Sub-types →
- Budd-Chiari syndrome 1 trial
- Nutmeg liver 1 trial
- Hepatic infarction 0 trials
- Hepatic vein thrombosis 0 trials
- Liver angiosarcoma 0 trials
- Peliosis hepatis 0 trials
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Coronary microvascular disorder 69 trials
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Vascular ectasia 4 trials · 67 incl. sub-types
5 sub-types
- Telangiectasis 13 trials · 45 incl. sub-types Sub-types →
- Familial multiple nevi flammei 12 trials
- Gastric antral vascular ectasia 3 trials
- Lymphangiectasis 3 trials Sub-types →
- Nevus anemicus 0 trials
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Vascular hemostatic disease 62 trials · 63 incl. sub-types
2 sub-types
- Cavernous hemangioma 1 trial Sub-types →
- Shwartzman phenomenon 0 trials
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Lymphatic malformation 17 trials · 56 incl. sub-types
28 sub-types
- Noonan syndrome 22 trials · 25 incl. sub-types Sub-types →
- Lymphatic malformation 5 8 trials
- Anhidrotic ectodermal dysplasia-immunodeficiency-osteopetrosis-lymphedema syndrome 4 trials
- Lymphatic malformation 12 2 trials
- MPI-congenital disorder of glycosylation 1 trial
- Deafness-lymphedema-leukemia syndrome 1 trial
- Dahlberg-Borer-Newcomer syndrome 0 trials
- Hennekam syndrome 0 trials Sub-types →
- Norman-Roberts syndrome 0 trials
- Campomelia, Cumming type 0 trials
- Congenital primary lymphedema of Gordon 0 trials
- Hypotrichosis-lymphedema-telangiectasia syndrome 0 trials
- Hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 0 trials
- Lymphatic malformation 1 0 trials
- Lymphatic malformation 10 0 trials
- Lymphatic malformation 11 0 trials
- Lymphatic malformation 13 0 trials
- Lymphatic malformation 14 0 trials
- Lymphatic malformation 2 0 trials
- Lymphatic malformation 3 0 trials
- Lymphatic malformation 4 0 trials
- Lymphatic malformation 6 0 trials
- Lymphatic malformation 7 0 trials
- Lymphatic malformation 8 0 trials
- Lymphatic malformation 9 0 trials
- Lymphedema-distichiasis syndrome 0 trials
- Microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability 0 trials
- Yellow nail syndrome 0 trials
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Capillary malformation 4 trials · 49 incl. sub-types
6 sub-types
- Hereditary hemorrhagic telangiectasia 34 trials Sub-types →
- Familial multiple nevi flammei 12 trials
- Capillary malformation-arteriovenous malformation syndrome 3 trials Sub-types →
- Angioma serpiginosum 0 trials Sub-types →
- Cutis marmorata telangiectatica congenita 0 trials
- Stork bite 0 trials
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Vascular malformation 32 trials · 34 incl. sub-types
6 sub-types
- Congenital vascular malformation 1 trial · 2 incl. sub-types Sub-types →
- EPHB4-associated vascular malformation spectrum 0 trials Sub-types →
- Cerebral proliferative angiopathy 0 trials
- Fibro-adipose vascular anomaly 0 trials
- Glomuvenous malformation 0 trials
- Splenic venous malformation 0 trials
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Patent ductus arteriosus 28 trials
4 sub-types
- Char syndrome 0 trials
- PDA1 0 trials
- Patent ductus arteriosus 2 0 trials
- Patent ductus arteriosus 3 0 trials
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Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 16 trials · 19 incl. sub-types
3 sub-types
- Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 19 trials
- Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2 0 trials Sub-types →
- Cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 1 0 trials
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Lymphatic vessel neoplasm 0 trials · 15 incl. sub-types
1 sub-type
- Lymphangioma 5 trials · 15 incl. sub-types Sub-types →
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Familial thoracic aortic aneurysm and aortic dissection 11 trials · 12 incl. sub-types
9 sub-types
- Aortic aneurysm, familial thoracic 1 1 trial
- Aortic aneurysm, familial thoracic 9 1 trial
- Aortic aneurysm, familial thoracic 10 0 trials
- Aortic aneurysm, familial thoracic 12 0 trials
- Aortic aneurysm, familial thoracic 2 0 trials
- Aortic aneurysm, familial thoracic 4 0 trials
- Aortic aneurysm, familial thoracic 6 0 trials
- Aortic aneurysm, familial thoracic 7 0 trials
- Aortic aneurysm, familial thoracic 8 0 trials
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Thoracic outlet syndrome 11 trials
3 sub-types
- Arterial thoracic outlet syndrome 0 trials
- Neurogenic thoracic outlet syndrome 0 trials
- Venous thoracic outlet syndrome 0 trials
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Calciphylaxis 9 trials
2 sub-types
- Calciphylaxis cutis 0 trials
- Visceral calciphylaxis 0 trials
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Arterial calcification of infancy 7 trials
2 sub-types
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2 sub-types
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Loeys-Dietz syndrome 6 trials
6 sub-types
- Loeys-Dietz syndrome 1 0 trials
- Loeys-Dietz syndrome 2 0 trials
- Loeys-Dietz syndrome 4 0 trials
- Loeys-Dietz syndrome 6 0 trials
- Rienhoff syndrome 0 trials
- Aneurysm-osteoarthritis syndrome 0 trials
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Angioosteohypertrophic syndrome 6 trials
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Congenital portosystemic shunt 4 trials
1 sub-type
- Patent ductus venosus 0 trials
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Capillary disorder 0 trials · 4 incl. sub-types
4 sub-types
- Gastric antral vascular ectasia 3 trials
- Capillary leak syndrome 1 trial
- Breast angiomatosis 0 trials
- Capillary lymphangioma 0 trials
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Angiodysplasia 2 trials · 3 incl. sub-types
2 sub-types
- Angiodysplasia of intestine 1 trial
- Angiodysplasia of stomach 0 trials
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2 sub-types
- Moyamoya disease 5 0 trials
- Aortic aneurysm, familial thoracic 6 0 trials
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Superior vena cava syndrome 2 trials
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Arterial tortuosity syndrome 1 trial
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6 sub-types
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Bleeding disorder, vascular-type 0 trials
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Cholesterol embolism 0 trials
2 sub-types
- Atheroembolism of kidney 0 trials
- Blue toe syndrome 0 trials
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Congenital anomaly of hepatic vein 0 trials
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7 sub-types
- Absence of innominate vein 0 trials
- Agenesis of the superior vena cava 0 trials
- Left superior vena cava persisting to left-sided atrium 0 trials
- Persistent left superior vena cava connecting to the left-sided atrium 0 trials
- Primary superior vena cava aneurysm 0 trials
- Right superior vena cava connecting to left-sided atrium 0 trials
- Subaortic course of innominate vein 0 trials
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Congenital renal artery stenosis 0 trials
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Coronary sinus atresia 0 trials
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Coronary sinus stenosis 0 trials
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Fibrocartilaginous embolism 0 trials
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Internal carotid agenesis 0 trials
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Ischemic colitis 0 trials
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Neonatal Marfan syndrome 0 trials
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Pulmonary venoocclusive disease 0 trials
2 sub-types
- Pulmonary venoocclusive disease 1 0 trials
- Pulmonary venoocclusive disease 2 0 trials
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Segmental arterial mediolysis 0 trials
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Vascular disorder of penis 0 trials
Most studied deeper sub-types
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Heart transplant patients get new weapon against hidden artery damage
Disease control CompletedThis study tested the drug alirocumab in 114 heart transplant recipients to see if it safely reduces plaque buildup in the new heart's arteries. The drug targets a protein called PCSK9 to lower harmful cholesterol. Researchers measured changes in artery plaque using ultrasound at…
Phase 2 • Sponsor: Stanford University • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Can pushing blood pressure lower save stroke Survivors' hearts?
Disease control CompletedThis study tests whether a very low blood pressure target (below 120 mmHg) can prevent major heart problems in people who have had a stroke or mini-stroke. About 4,300 participants are randomly assigned to either intensive or standard blood pressure control and followed for about…
Sponsor: Hospital Israelita Albert Einstein • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Can a bone marrow stimulant help people with leg artery disease walk farther?
Disease control CompletedThis study tested whether a drug called GM-CSF can improve symptoms and blood flow in people with peripheral artery disease (PAD), a condition where plaque narrows leg arteries, causing pain and limiting walking. 151 participants received either GM-CSF or a placebo for two 3-week…
Phase 2 • Sponsor: Emory University • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Can a new device suck out deadly lung clots?
Disease control CompletedThis trial tests a device called the Symphony Thrombectomy System in people with acute pulmonary embolism, a condition where blood clots block arteries in the lungs. The device is designed to restore blood flow by suctioning out or breaking up the clots. The study will check how …
Sponsor: Imperative Care, Inc. • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New procedure shows promise for Hard-to-Control high blood pressure
Disease control CompletedThis study tested a procedure called renal denervation, which uses radiofrequency energy to calm overactive nerves in the kidneys, to see if it can safely lower blood pressure in people whose hypertension is not controlled by up to three medications. The study involved 337 partic…
Sponsor: Medtronic Vascular • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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New PAH pill aims to delay worsening in large trial
Disease control CompletedThis study tested a new oral drug called ralinepag in 687 adults with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work harder. Participants took ralinepag or a placebo on top of their usual PAH medications. The main goal was to see if rali…
Phase 3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a vacuum dressing save amputation patients from more surgery?
Disease control CompletedThis study tested whether a special vacuum dressing (negative pressure wound therapy) helps wounds heal better after major leg amputations. 158 adults who had a leg amputation (not due to injury) took part. The goal was to see if this dressing reduces problems like infection, reo…
Sponsor: University of Southern Denmark • Aim: Disease control
Last updated Jun 27, 2026 13:08 UTC
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Can tighter blood pressure control after pregnancy save lives?
Disease control CompletedThis study tested whether a stricter blood pressure goal (below 135/85) after a pregnancy complicated by high blood pressure is better than the usual care (below 150/100). About 60 new mothers were enrolled and followed for six months. The goal is to see if tighter control is pos…
Phase 4 • Sponsor: Alisse Hauspurg • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New device aims to pull clots from the brain in major strokes
Disease control CompletedThis completed study tested a new device called the Supernova stent retriever in 55 people with severe stroke caused by a large blood clot in the brain. The device is threaded through blood vessels to grab and remove the clot, restoring blood flow. Researchers measured how often …
Sponsor: Gravity Medical Technology, INC • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Friends and family may be key to preventing second strokes
Disease control CompletedThis study tested whether using social networks (like family and friends) can help people at high risk for stroke stick to their medications and control risk factors after leaving the hospital. Researchers enrolled 720 patients and compared standard care with a social network-bas…
Sponsor: Changhai Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New stent helps people with leg artery disease walk better and feel better
Disease control CompletedThis study looked at how well the ELUVIA drug-coated stent works in real-world patients with blocked arteries in the thigh or knee area. A total of 291 adults received the stent and were followed for two years. The main goal was to see if their quality of life and walking ability…
Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New drug aims to tame blood vessel inflammation without steroids
Disease control CompletedThis study tested the drug secukinumab (Cosentyx) in 151 adults with newly diagnosed giant cell arteritis, a condition causing inflamed blood vessels. Participants were in remission and received either secukinumab or a placebo, along with a steroid taper. The goal was to see if s…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Can a simple device keep blood flowing and prevent dangerous clots?
Disease control CompletedThis completed trial tested a device called Ceragem Master V6 to see if it improves blood circulation in people at risk for deep vein thrombosis (DVT) and in healthy adults. 59 participants used the device once, and researchers measured changes in blood flow speed and vein size u…
Sponsor: Ceragem Clinical Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New device aims to boost circulation and ward off dangerous clots
Disease control CompletedThis completed trial tested a device called CGM MB-1701 to see if it can improve blood flow in people at risk for deep vein thrombosis (DVT). The study enrolled 60 adults who did not have DVT at the start. Researchers measured changes in blood flow speed in the leg vein after usi…
Sponsor: Ceragem Clinical Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New drug shows promise for Hard-to-Treat blood cancer
Disease control CompletedThis study tested a drug called elranatamab in 39 Chinese patients with multiple myeloma that had stopped responding to at least three prior treatments. The drug works by helping the immune system attack cancer cells. The goal was to see if it could shrink tumors and control the …
Phase 2 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New device shows promise for aneurysm repair in pelvic arteries
Disease control CompletedThis study looked at how well a special stent (the Gore IBE device) works in real-world use for people with bulging blood vessels (aneurysms) in the belly or pelvis. Researchers tracked 100 patients who already had the device implanted to check if it stayed open and kept the aneu…
Sponsor: Rijnstate Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New hope for rare eye disease: personalized drug schedule shows promise
Disease control CompletedThis study tested a personalized treatment plan using the drug brolucizumab for people with a specific eye condition called polypoidal choroidal vasculopathy (PCV). The goal was to see if adjusting the treatment schedule based on each person's needs could maintain or improve visi…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Heart patients get Double-Duty blood thinners in massive trial
Disease control CompletedThis completed trial tested whether taking two blood thinners (clopidogrel and aspirin) for 12 months after a heart stent procedure is better than aspirin alone for people with multiple blocked coronary arteries. Over 8,000 patients were enrolled across 100 centers. The main goal…
Phase 4 • Sponsor: Harbin Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Heart artery study tests smarter imaging to prevent attacks
Disease control CompletedThis study tested whether adding a special pressure wire measurement (FFR) to standard angiography helps doctors decide the best treatment for people with multiple blocked heart arteries. Over 900 patients were randomly assigned to get either angiography alone or angiography plus…
Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Stem cells injected before amputation aim to prevent further surgery
Disease control CompletedThis study tested whether injecting donor stem cells into the leg muscles before amputation could prevent wound problems and reduce the need for more amputations. 81 people scheduled for leg amputation due to poor blood flow took part. The main goal was to check safety, not yet t…
Phase 1 • Sponsor: Indiana University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New algorithm could spare cancer patients unnecessary CT scans for blood clots
Diagnosis CompletedThis study tested whether a simple checklist and blood test (the YEARS algorithm) can safely rule out pulmonary embolism (a blood clot in the lungs) in people with active cancer, compared to the standard approach of doing a CT scan on everyone. About 700 cancer patients with susp…
Sponsor: Leiden University Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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Could a phone app help parents of kids with special needs thrive?
Symptom relief CompletedThis trial tests a 12-week smartphone-based program called PACT, which combines acceptance and commitment training with positive parenting advice, for parents of children with special health care needs. The goal is to see if it can improve parents' mental well-being, psychologica…
Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Watching videos before surgery may ease nerves, study finds
Symptom relief CompletedThis study tested whether giving vascular surgery patients access to a website with educational videos could reduce their anxiety before the operation. 250 patients were split into two groups: one got the videos, the other did not. Researchers measured anxiety using a simple 0-to…
Sponsor: Centre Chirurgical Marie Lannelongue • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New inhaled drug shows promise for easing lung pressure in rare Heart-Lung condition
Symptom relief CompletedThis study tested an inhaled medication called RT234 in 14 adults with pulmonary arterial hypertension (PAH), a condition where blood pressure in the lungs is dangerously high. The goal was to see if the drug could quickly lower lung blood pressure during a heart catheterization …
Phase 2 • Sponsor: Respira Therapeutics, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Ear-Zapping device shows promise for lupus fatigue
Symptom relief CompletedThis study tested a non-invasive device that stimulates the vagus nerve through the ear to see if it can reduce fatigue in people with lupus. 75 participants received either active or sham stimulation over two phases. The main goal was to measure changes in fatigue using a standa…
Sponsor: Rigshospitalet, Denmark • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Gene hunt: scientists probe rare connective tissue variants
Knowledge-focused CompletedThis completed study looked at 32 people with known genetic changes in connective tissue genes to better understand how these changes affect overall health. Participants underwent a range of medical tests and exams over 3-5 days. The goal was to gather information, not to test a …
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Leg blood flow study reveals clues about stroke recovery
Knowledge-focused CompletedThis study looked at how blood moves through leg muscles in people who have had a stroke compared to healthy adults. Researchers used gentle leg movements and muscle contractions to measure blood flow. The goal was to learn more about why stroke survivors often have reduced exerc…
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Cancer drug heart risk mystery probed in new study
Knowledge-focused CompletedThis study looked at how immune checkpoint inhibitors, a type of cancer drug, might affect blood vessels and increase heart risks. Researchers measured blood vessel function and checked for related markers in 39 cancer patients before and after starting treatment. The goal was to…
Sponsor: Institut Mutualiste Montsouris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Heart health mystery: does mitochondria fuel racial gap?
Knowledge-focused CompletedThis study looked at whether tiny cell parts called mitochondria contribute to higher blood pressure and worse blood vessel health in Black adults. Researchers gave 31 middle-aged and older adults a supplement called MitoQ or a placebo for 8 weeks. The goal was to understand the …
Sponsor: Auburn University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Inhaled ED drug tested for safety in healthy people
Knowledge-focused CompletedThis early-phase trial tested the safety and how the body processes an inhaled form of vardenafil (RT234) in 31 healthy adults. Participants received single and multiple doses of the drug via an inhaler or as a pill. The study is complete and focused on side effects and drug leve…
Phase 1 • Sponsor: Respira Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Scientists adapt earthquake imaging to peek inside human bones
Knowledge-focused CompletedThis completed study tested a new ultrasound technique to detect blood flow inside solid bone, which standard ultrasound cannot see. Nineteen healthy volunteers had ultrasound scans of their forearm and shin bone while blood flow was changed using a blood pressure cuff or by chan…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:52 UTC