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Scientists adapt earthquake imaging to peek inside human bones

NCT ID NCT04396288

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested a new ultrasound technique to detect blood flow inside solid bone, which standard ultrasound cannot see. Nineteen healthy volunteers had ultrasound scans of their forearm and shin bone while blood flow was changed using a blood pressure cuff or by changing body position. The goal was to see if this method, borrowed from earthquake imaging, could reliably measure blood movement inside bone, which may help understand and diagnose bone diseases like osteoporosis in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this new ultrasound technique could help doctors better understand and diagnose bone diseases like osteoporosis by seeing blood flow inside bone.
What could go wrong
This was a very small, early study in healthy people, not patients. The method is still experimental and may not work reliably in real-world medical settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

19 people

The number who actually took part.

Started

Sep 2021

Finished

Jan 2024

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * be 18 years old or older * speaks good French * have an affiliation to a French Healthcare system (health insurance) * sign the informed consent Exclusion Criteria: * bone fracture at the tibia or at the forearm less than one year ago * injury or wound still present at the tibia or at the forearm * pregnant women * protected persons

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic metabolic bone disorder vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood circulation disorder Bone diseases, metabolic

Contacts and locations

Locations

  • Service de Radiologie polyvalente et oncologique, hôpital La Pitié-Salpêtrière

    Paris, France

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