Heart health mystery: does mitochondria fuel racial gap?
NCT ID NCT05561556
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether tiny cell parts called mitochondria contribute to higher blood pressure and worse blood vessel health in Black adults. Researchers gave 31 middle-aged and older adults a supplement called MitoQ or a placebo for 8 weeks. The goal was to understand the role of mitochondria in racial health differences, not to treat or cure any disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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31 people
The number who actually took part.
- Started
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Dec 2022
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Are between the ages of 45-75 * Have blood pressure no higher than 150/90 mmHg * Have a BMI less than 40 Kg/m2 (otherwise healthy) * Free from metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD \& cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular) * Free of any medical issues that prevent participants from exercising (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis), giving blood (i.e., blood thinners), or allergies associated with MitoQ substances. Exclusion Criteria: * Known allergy to MitoQ * High blood pressure - greater the 150/90 mmHg * Low blood pressure - less than 90/50 mmHg * History of cardiovascular disease * History of cancer * History of diabetes * History of kidney disease * Obesity (BMI \> 40 kg/m2) * Current pregnancy * Nursing mothers * Communication barriers
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Auburn University
Auburn, Alabama, 36849, United States
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Other studies related to the condition(s) this trial covers.
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