Respiratory system disorder
MONDO:0005087A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.
Also known as: disease of respiratory system, disease or disorder of respiratory system, disorder of respiratory system, respiratory disease, respiratory disorder, respiratory system disease, respiratory system disease or disorder, respiratory system disorder
10848 clinical trials for this condition and its sub-types, 150 tagged with Respiratory system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Respiratory system disorder
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Lower respiratory tract disorder 18 trials · 7,938 incl. sub-types
5 sub-types
- Lung disorder 251 trials · 7,078 incl. sub-types Sub-types →
- Tracheal disorder 6 trials · 1,088 incl. sub-types Sub-types →
- Bronchial disorder 19 trials · 1,010 incl. sub-types Sub-types →
- Pleural disorder 15 trials · 177 incl. sub-types Sub-types →
- Tracheobronchitis 5 trials · 55 incl. sub-types Sub-types →
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Respiratory system cancer 6 trials · 4,516 incl. sub-types
9 sub-types
- Lung cancer 1,207 trials · 3,941 incl. sub-types Sub-types →
- Pharynx cancer 10 trials · 495 incl. sub-types Sub-types →
- Larynx cancer 41 trials · 125 incl. sub-types Sub-types →
- Pleural cancer 9 trials · 83 incl. sub-types Sub-types →
- Bronchus cancer 3 trials · 26 incl. sub-types Sub-types →
- Paranasal sinus cancer 4 trials · 24 incl. sub-types Sub-types →
- Nasal cavity cancer 5 trials · 14 incl. sub-types Sub-types →
- SMARCA4-deficient sarcoma of thorax 8 trials
- Tracheal cancer 0 trials · 1 incl. sub-types Sub-types →
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Respiratory tract neoplasm 32 trials · 4,437 incl. sub-types
8 sub-types
- Lung neoplasm 1,367 trials · 4,039 incl. sub-types Sub-types →
- Nasopharyngeal neoplasm 37 trials · 226 incl. sub-types Sub-types →
- Laryngeal neoplasm 72 trials · 138 incl. sub-types Sub-types →
- Pleural neoplasm 5 trials · 97 incl. sub-types Sub-types →
- Bronchial neoplasm 20 trials · 38 incl. sub-types Sub-types →
- Nasal cavity neoplasm 1 trial · 15 incl. sub-types Sub-types →
- SMARCA4-deficient sarcoma of thorax 8 trials
- Trachea neoplasm 2 trials · 5 incl. sub-types Sub-types →
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Upper respiratory tract disorder 5 trials · 1,848 incl. sub-types
10 sub-types
- Tracheal disorder 6 trials · 1,088 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Laryngeal disorder 44 trials · 259 incl. sub-types Sub-types →
- Nasal cavity disorder 3 trials · 224 incl. sub-types Sub-types →
- Pharyngitis 34 trials · 43 incl. sub-types Sub-types →
- Tonsillitis 23 trials · 27 incl. sub-types Sub-types →
- Adenoid hypertrophy 22 trials
- Epiglottitis 1 trial Sub-types →
- Acute laryngopharyngitis 0 trials
- Uvulitis 0 trials
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Respiratory tract infectious disorder 174 trials · 1,330 incl. sub-types
14 sub-types
- Pneumonia 326 trials · 610 incl. sub-types Sub-types →
- Viral respiratory tract infection 47 trials · 564 incl. sub-types Sub-types →
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Streptococcal sore throat 8 trials
- Pleural tuberculosis 7 trials Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Lung abscess 3 trials
- Pneumonic plague 3 trials
- Tuberculous fibrosis of lung 3 trials
- Laryngeal diphtheria 0 trials
- Laryngeal tuberculosis 0 trials
- Nasopharyngeal diphtheria 0 trials
- Silicotuberculosis 0 trials
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Sleep apnea syndrome 214 trials · 600 incl. sub-types
2 sub-types
- Obstructive sleep apnea syndrome 516 trials · 517 incl. sub-types Sub-types →
- Central sleep apnea syndrome 21 trials · 23 incl. sub-types Sub-types →
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Disorder of pharynx 3 trials · 596 incl. sub-types
10 sub-types
- Pharynx cancer 10 trials · 495 incl. sub-types Sub-types →
- Neoplasm of oropharynx 3 trials · 279 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Neoplasm of hypopharynx 0 trials · 100 incl. sub-types Sub-types →
- Takayasu arteritis 27 trials
- Tonsillitis 23 trials · 27 incl. sub-types Sub-types →
- Tonsil neoplasm 0 trials · 8 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
- Epiglottitis 1 trial Sub-types →
- Oropharyngeal anthrax 0 trials
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Cystic fibrosis 283 trials
1 sub-type
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Allergic respiratory disease 2 trials · 218 incl. sub-types
4 sub-types
- Allergic rhinitis 96 trials · 140 incl. sub-types Sub-types →
- Allergic asthma 41 trials Sub-types →
- Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types Sub-types →
- Allergic bronchopulmonary aspergillosis 15 trials Sub-types →
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Paranasal sinus disorder 12 trials · 162 incl. sub-types
7 sub-types
- Sinusitis 44 trials · 130 incl. sub-types Sub-types →
- Paranasal sinus neoplasm 5 trials · 29 incl. sub-types Sub-types →
- Maxillary sinus cholesteatoma 0 trials
- Polyp of ethmoidal sinus 0 trials
- Polyp of frontal sinus 0 trials
- Polyp of maxillary sinus 0 trials
- Polyp of sphenoidal sinus 0 trials
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Perinatal asphyxia 152 trials
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Pulmonary tuberculosis 107 trials · 110 incl. sub-types
3 sub-types
- Tuberculous fibrosis of lung 3 trials
- Primary pulmonary tuberculosis 0 trials
- Silicotuberculosis 0 trials
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Bronchopulmonary dysplasia 96 trials
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Diaphragm disorder 27 trials · 91 incl. sub-types
5 sub-types
- Congenital diaphragmatic hernia 45 trials Sub-types →
- Respiratory paralysis 20 trials
- Diaphragmatic eventration 3 trials
- Diaphragmatic malformation 1 trial
- Diaphragmitis 0 trials
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Altitude sickness 54 trials · 56 incl. sub-types
2 sub-types
- Acute mountain sickness 7 trials
- Chronic mountain sickness 3 trials
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Alpha 1-antitrypsin deficiency 44 trials
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Pertussis 39 trials
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Primary ciliary dyskinesia 34 trials
59 sub-types
- Primary ciliary dyskinesia 1 6 trials
- CFAP46-related primary ciliary dyskinesia 0 trials
- Stromme syndrome 0 trials
- Ciliary discoordination due to random ciliary orientation 0 trials
- Ciliary dyskinesia with defective radial spokes 0 trials
- Ciliary dyskinesia with excessively long cilia 0 trials
- Ciliary dyskinesia with transposition of ciliary microtubules 0 trials
- Ciliary dyskinesia, primary, 36, X-linked 0 trials
- Ciliary dyskinesia, primary, 37 0 trials
- Ciliary dyskinesia, primary, 38 0 trials
- Ciliary dyskinesia, primary, 39 0 trials
- Ciliary dyskinesia, primary, 40 0 trials
- Ciliary dyskinesia, primary, 41 0 trials
- Ciliary dyskinesia, primary, 42 0 trials
- Ciliary dyskinesia, primary, 43 0 trials
- Ciliary dyskinesia, primary, 44 0 trials
- Ciliary dyskinesia, primary, 45 0 trials
- Ciliary dyskinesia, primary, 46 0 trials
- Ciliary dyskinesia, primary, 47, and lissencephaly 0 trials
- Ciliary dyskinesia, primary, 48, without situs inversus 0 trials
- Ciliary dyskinesia, primary, 49, without situs inversus 0 trials
- Ciliary dyskinesia, primary, 50 0 trials
- Ciliary dyskinesia, primary, 51 0 trials
- Ciliary dyskinesia, primary, 52 0 trials
- Ciliary dyskinesia, primary, 53 0 trials
- Ciliary dyskinesia, primary, 54 0 trials
- Primary ciliary dyskinesia 10 0 trials
- Primary ciliary dyskinesia 11 0 trials
- Primary ciliary dyskinesia 12 0 trials
- Primary ciliary dyskinesia 13 0 trials
- Primary ciliary dyskinesia 14 0 trials
- Primary ciliary dyskinesia 15 0 trials
- Primary ciliary dyskinesia 16 0 trials
- Primary ciliary dyskinesia 17 0 trials
- Primary ciliary dyskinesia 18 0 trials
- Primary ciliary dyskinesia 19 0 trials
- Primary ciliary dyskinesia 2 0 trials
- Primary ciliary dyskinesia 20 0 trials
- Primary ciliary dyskinesia 21 0 trials
- Primary ciliary dyskinesia 22 0 trials
- Primary ciliary dyskinesia 23 0 trials
- Primary ciliary dyskinesia 24 0 trials
- Primary ciliary dyskinesia 25 0 trials
- Primary ciliary dyskinesia 26 0 trials
- Primary ciliary dyskinesia 27 0 trials
- Primary ciliary dyskinesia 28 0 trials
- Primary ciliary dyskinesia 29 0 trials
- Primary ciliary dyskinesia 3 0 trials
- Primary ciliary dyskinesia 30 0 trials
- Primary ciliary dyskinesia 32 0 trials
- Primary ciliary dyskinesia 33 0 trials
- Primary ciliary dyskinesia 34 0 trials
- Primary ciliary dyskinesia 35 0 trials
- Primary ciliary dyskinesia 4 0 trials
- Primary ciliary dyskinesia 5 0 trials
- Primary ciliary dyskinesia 6 0 trials
- Primary ciliary dyskinesia 7 0 trials
- Primary ciliary dyskinesia 8 0 trials
- Primary ciliary dyskinesia 9 0 trials
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Severe acute respiratory syndrome 30 trials
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Infantile apnea 5 trials · 22 incl. sub-types
1 sub-type
- Apnea of prematurity 20 trials
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Recurrent respiratory papillomatosis 8 trials · 9 incl. sub-types
1 sub-type
- Laryngeal papillomatosis 1 trial
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Respiratory system benign neoplasm 1 trial · 8 incl. sub-types
15 sub-types
- Benign laryngeal neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Benign neoplasm of trachea 0 trials · 2 incl. sub-types Sub-types →
- Lung benign neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Benign neoplasm of nasal cavity 1 trial Sub-types →
- Benign neoplasm of ethmoidal sinus 0 trials Sub-types →
- Benign neoplasm of frontal sinus 0 trials Sub-types →
- Benign neoplasm of hypopharynx 0 trials Sub-types →
- Benign neoplasm of maxillary sinus 0 trials Sub-types →
- Benign neoplasm of nasopharynx 0 trials
- Benign neoplasm of oropharynx 0 trials
- Benign neoplasm of pleura 0 trials Sub-types →
- Benign neoplasm of sphenoidal sinus 0 trials Sub-types →
- Benign neoplasm of tonsil 0 trials Sub-types →
- Endobronchial lipoma 0 trials
- Paranasal sinus Schneiderian papilloma 0 trials Sub-types →
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Respiratory or thoracic malformation 0 trials · 8 incl. sub-types
1 sub-type
- Thoracic malformation 1 trial · 8 incl. sub-types Sub-types →
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Pulmonary hypoplasia 7 trials
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Reactive airway disease 5 trials
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2 sub-types
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5 sub-types
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Young syndrome 2 trials
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Diffuse alveolar hemorrhage 2 trials
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Plastic bronchitis 2 trials
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Middle East respiratory syndrome 1 trial
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Bronchogenic cyst 1 trial
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3 sub-types
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16q24.1 microdeletion syndrome 0 trials
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IgG4-related mediastinitis 0 trials
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Mounier-Kuhn syndrome 0 trials
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Siegler-Brewer-Carey syndrome 0 trials
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Williams-Campbell syndrome 0 trials
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Acinar dysplasia 0 trials
3 sub-types
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Bronchiectasis and nasal polyposis 0 trials
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Congenital bronchobiliary fistula 0 trials
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Eosinophilic granuloma 0 trials
1 sub-type
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Isolated left bronchial isomerism 0 trials
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Laryngo-onycho-cutaneous syndrome 0 trials
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Mucopolysaccharidosis-plus syndrome 0 trials
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Pulmonary agenesis 0 trials
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Staphylococcal necrotizing pneumonia 0 trials
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Tracheal agenesis 0 trials
Most studied deeper sub-types
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Can an updated COVID-19 vaccine keep up with the virus?
Vaccine Recruiting nowThis trial is testing an updated version of the BNT162b2 COVID-19 vaccine in healthy adults aged 18 to 64. Participants will receive either the updated COVID-19 vaccine or a Tdap vaccine (for tetanus, diphtheria, and whooping cough) to compare safety and measure spike protein lev…
Phase 4 • Sponsor: BioNTech SE • Aim: Vaccine
Last updated Aug 09, 2026 00:00 UTC
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New hope for KRAS lung cancer: major trial launches for targeted combo therapy
Disease control Recruiting nowThis global study is testing whether adding the experimental drug olomorasib to standard immunotherapy and chemotherapy can help people with a specific genetic subtype of advanced non-small cell lung cancer (KRAS G12C mutation). About 1,264 participants will receive either the ne…
Phase 3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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App alerts COPD patients when their inhalers may be out of date
Disease control Recruiting nowThis trial tests whether a smartphone app can help people with COPD achieve better symptom control by flagging when their inhaled medications may not match current guidelines. Participants use the app to record symptoms and medications. Some receive alerts if their prescriptions …
Phase 1 • Sponsor: University of Southampton • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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New combo therapy aims to control returning lung cancer in targeted patients
Disease control Recruiting nowThis study is for people with a specific type of lung cancer (EGFR-mutant) that has spread to other parts of the body after they finished a previous treatment (osimertinib). The goal is to see if combining osimertinib with chemotherapy can help control the cancer for longer. Abou…
Phase 4 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New drug AIR-001 enters first human tests for rare lung condition
Disease control Recruiting nowThis early-stage trial tests a new drug called AIR-001 in 54 adults with alpha-1 antitrypsin deficiency (AATD) who have a specific genetic type (PiZZ). The study aims to check safety and how the body processes the drug. Participants receive increasing doses of AIR-001 under the s…
Phase 1 • Sponsor: AIRNA Corporation • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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New pill aims to keep High-Risk COVID patients out of the hospital
Disease control Recruiting nowThis study tests an oral medication called ibuzatrelvir in adults and teens with COVID-19 who are not hospitalized but have a high risk of becoming severely ill. Participants will receive either the drug or a placebo for 5 days, and researchers will track whether it reduces emerg…
Phase 3 • Sponsor: Pfizer • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Could a simple shot replace IV drips for Alpha-1 patients?
Disease control Recruiting nowThis study tests a new way to give Alpha1-Proteinase Inhibitor—a medicine that helps protect the lungs in people with Alpha-1 Antitrypsin Deficiency. Instead of getting it through a vein at a clinic, participants will receive it as a weekly injection under the skin. The trial wil…
Phase 3 • Sponsor: Grifols Therapeutics LLC • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Can exercise rebuild lungs damaged by dust?
Disease control Recruiting nowThis trial tests whether aerobic exercise or resistance exercise can improve lung function in male quarry workers who have breathing problems from years of dust exposure. Participants will be randomly assigned to one of three groups: aerobic training, resistance training, or a co…
Sponsor: Cairo University • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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New drug combo targets hard-to-treat cancers with KRAS mutation
Disease control Recruiting nowThis study tests two experimental drugs, elironrasib and daraxonrasib, given alone or together, in people with advanced solid tumors that have a specific KRAS G12C mutation. The goal is to see if the drugs are safe and can shrink or control the cancer. About 534 adults with lung,…
Phase 1/2 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Could a 2-Month TB cure replace 6 months of pills for kids?
Disease control Recruiting nowThis study tests whether a 2-month combination of four drugs can cure drug-susceptible tuberculosis in children under 10 as safely and effectively as the standard 4- to 6-month regimen. Researchers will enroll 860 children, including those with HIV, to compare the shorter treatme…
Phase 3 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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New inhaled therapy for lung blood pressure passes first safety hurdle
Disease control Recruiting nowThis early-stage trial tests the safety of a single inhaled dose of L608 in 32 healthy volunteers. L608 is a liposomal formulation designed to treat pulmonary arterial hypertension, a condition of high blood pressure in the lungs. The study compares different doses against a plac…
Phase 1 • Sponsor: Pharmosa Biopharm Inc. • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Human milk mouth care may shield preemies from lung infections
Disease control Recruiting nowThis study investigates whether cleaning the mouths of very low birth weight premature infants with human milk several times a day can reduce harmful bacteria and lower the risk of lung complications like pneumonia and bronchopulmonary dysplasia. Researchers will follow 168 babie…
Sponsor: University of Florida • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Can a night-time breathing device boost brain power in older vets with lung and sleep troubles?
Disease control Recruiting nowThis study looks at whether using a positive airway pressure (PAP) machine at night can improve thinking, sleepiness, and quality of life in older veterans (age 60+) who have both COPD and obstructive sleep apnea—a combination called Overlap Syndrome. About 668 participants will …
Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New targeted drug shows promise for Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new drug called repotrectinib in people with advanced solid tumors that have certain gene changes (ALK, ROS1, or NTRK). The trial has two parts: first, finding a safe dose, and second, seeing how well the drug shrinks tumors. About 500 adults with advanced canc…
Phase 1/2 • Sponsor: Turning Point Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Blood thinners may be unnecessary for minor lung clots, new trial suggests
Disease control Recruiting nowThis study compares two approaches for low-risk patients with small blood clots in the lungs (isolated subsegmental pulmonary embolism). Half will receive standard blood-thinning medication (rivaroxaban), while the other half will get a placebo and be closely monitored. The goal …
Phase 4 • Sponsor: Drahomir Aujesky • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New asthma drug shows promise in Mid-Stage trial
Disease control Recruiting nowThis study tests a new medicine called PF-07275315 for adults with moderate-to-severe asthma that is not well controlled. Participants will receive either the drug or a placebo as injections over 12 weeks. The goal is to see if the drug improves lung function and is safe. About 2…
Phase 2 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Lung cancer showdown: surgery vs. radiation – which is better?
Disease control Recruiting nowThis study looks at two standard treatments for early-stage lung cancer: surgery and a precise type of radiation called stereotactic radiotherapy. About 670 veterans with stage I non-small cell lung cancer will take part. The goal is to see which treatment leads to longer surviva…
Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Can a 9-Minute chat help black adults breathe easier?
Disease control Recruiting nowThis study tests a short, scripted conversation between doctors and Black adults with uncontrolled asthma. The goal is to help patients and doctors make decisions together about asthma medicines. Researchers will enroll 400 adults at community health centers to see if this approa…
Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New drug vimseltinib aims to tame chronic GVHD in failed treatments
Disease control Recruiting nowThis study tests whether the drug vimseltinib is safe and effective for adults with moderate to severe chronic graft-versus-host disease (cGVHD) who have not improved after at least two prior treatments. About 48 participants will take vimseltinib daily for up to two years. The g…
Phase 2 • Sponsor: Deciphera Pharmaceuticals, LLC • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New pill for scarred lungs enters human testing
Disease control Recruiting nowThis study tests an experimental oral drug called INS018_055 in 40 adults with idiopathic pulmonary fibrosis (IPF), a disease that causes lung scarring and breathing difficulty. The main goal is to check the drug's safety over 12 weeks. Participants will be randomly assigned to r…
Phase 2 • Sponsor: InSilico Medicine Hong Kong Limited • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Inhaled xenon gas lights up the lungs on MRI
Diagnosis Recruiting nowResearchers are testing whether hyperpolarized xenon MRI can show how well lungs move gas between air sacs, tissue, and red blood cells. The study includes children and adults who have had or are being evaluated for a stem-cell transplant, people with rare lung diseases or gas-ex…
Phase 1/2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Diagnosis
Last updated Sep 18, 2026 00:00 UTC
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AI reads chest X-Rays in the ER to catch silent killers early
Diagnosis Recruiting nowThis study tests whether an AI program can help emergency doctors find undiagnosed heart failure, COPD, and cancer by analyzing chest X-rays. Researchers will compare diagnosis rates when doctors have access to the AI's findings versus when they don't. The trial involves 17,000 a…
Sponsor: NHS Greater Glasgow and Clyde • Aim: Diagnosis
Last updated Jun 27, 2026 13:02 UTC
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Breathing in xenon: a new way to see lung health without X-Rays?
Diagnosis Recruiting nowThis study is testing a special MRI technique that uses inhaled xenon gas to create detailed images of lung function. Researchers want to see how well it works in healthy children and adults, as well as in people with various breathing problems. Participants will inhale the gas a…
Phase 1/2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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Smart patch listens for wheezes: could it replace the stethoscope?
Diagnosis Recruiting nowThis study tests a small wearable device called AeviceMD that listens to lung sounds and detects wheezing. Researchers want to see if the device is as accurate as a doctor using a stethoscope. About 160 children and adults with asthma will participate. If successful, the device c…
Sponsor: Aevice Health Pte. Ltd. • Aim: Diagnosis
Last updated Jun 27, 2026 07:53 UTC
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Virtual reality vs. play cards: a new battle to calm Kids' inhaler fears
Symptom relief Recruiting nowThis trial tests whether virtual reality goggles or gaming cards can help reduce fear, anxiety, and stress-related changes in heart rate and oxygen levels in children aged 4 to 6 during inhaler treatment. Children receiving inhaler medication often feel scared and anxious, which …
Sponsor: Bandırma Onyedi Eylül University • Aim: Symptom relief
Last updated Aug 23, 2026 00:00 UTC
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New nasal device could help kids with down syndrome sleep soundly
Symptom relief Recruiting nowThis study tests a special nasal airway device (ssNPA) in 40 children with weak throat muscles and obstructive sleep apnea, including those with Down syndrome. The device is designed to keep the airway open during sleep without needing surgery. Researchers will measure how well i…
Sponsor: University of Michigan • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC
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A gentle touch against coughs and colds: could manual therapy shorten respiratory illness?
Symptom relief Recruiting nowThis study tests whether adding lymphatic pump osteopathic manipulative therapy (OMT) to standard care helps older adults recover faster from respiratory illnesses like bronchitis, sinusitis, or pneumonia. Participants aged 65 to 100 with a new respiratory diagnosis will receive …
Sponsor: Geisinger Clinic • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Cartoons and stories soothe Kids' fear during breathing treatments
Symptom relief Recruiting nowThis study looks at whether watching cartoons or listening to breath-synchronized interactive stories can help children aged 6-9 feel less afraid and more comfortable while using a nebulizer for breathing medication. About 96 children with respiratory conditions will be randomly …
Sponsor: Mersin University • Aim: Symptom relief
Last updated Jul 22, 2026 00:00 UTC
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Which cancer care model boosts quality of life? large trial seeks answers
Symptom relief Recruiting nowThis study compares two approaches to supportive cancer care for nearly 3,000 adults with cancer. One group gets information through email or their health record, while the other works one-on-one with a lay health worker over 12 months. The goal is to see which model better impro…
Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 12:26 UTC
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Spinal zap plus breathing drills may boost lung power after paralysis
Symptom relief Recruiting nowThis study tests whether a gentle electrical stimulation of the spinal cord, combined with breathing exercises, can improve lung function in people with chronic spinal cord injury. About 36 adults will be split into three groups: breathing training alone, stimulation alone, or bo…
Sponsor: University of Louisville • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Scientists scour lungs for clues to why some get infections
Knowledge-focused Recruiting nowThis study gathers fluid and tissue from the lungs and nose of healthy volunteers and people with a history of lung infections. Researchers will compare samples to find differences in immune function that might explain why some people are more prone to infections. Participants un…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Xenon gas MRI could revolutionize lung scans
Knowledge-focused Recruiting nowThis study is testing a special type of MRI that uses hyperpolarized xenon gas to create detailed images of lung function. Researchers want to see how well this method works in 100 healthy adults. Participants will inhale the gas and hold their breath for up to 16 seconds during …
Phase 1/2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Could a single injection of AMG 691 be safe and Well-Tolerated?
Knowledge-focused Recruiting nowThis phase 1 trial is testing a single dose of the investigational drug AMG 691 in healthy Chinese and Japanese adults aged 18 to 60. The goal is to understand how the drug moves through the body and to check its safety and tolerability. Participants will receive one subcutaneous…
Phase 1 • Sponsor: Amgen • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Can we predict and treat cancer wasting better? a new study investigates
Knowledge-focused Recruiting nowThis study is looking at why some people with advanced cancer lose weight and muscle, a condition called cachexia. Researchers will follow 800 patients with advanced lung, pancreatic, or colorectal cancer to see if there are distinct subtypes of cachexia based on symptoms, biomar…
Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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Hidden lung disease common in heart patients who smoke?
Knowledge-focused Recruiting nowThis study will check 1,000 smokers aged 40+ who visit heart doctors to see how many have undiagnosed COPD, a lung disease that often goes unnoticed. Participants will take a simple breathing test and answer a questionnaire. The goal is to find out how common hidden COPD is in th…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Scientists probe the mystery of breathlessness to unlock better treatments
Knowledge-focused Recruiting nowThis study aims to understand why breathlessness varies among people with different lung diseases like COPD, asthma, and ILD. Researchers will measure lung function, exercise ability, and breathing patterns in 75 participants (50 with lung disease and 25 healthy controls). The go…
Sponsor: University Hospitals, Leicester • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Is outdoor exercise safe for kids in polluted cities? new study aims to find out.
Knowledge-focused Recruiting nowThis study looks at how short-term exposure to air pollution affects children's breathing. Around 330 children from London schools will either take a science lesson or do physical education outdoors. Researchers will measure lung function and immune responses to see if exercising…
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Pneumonia's hidden heart risk: new study tracks Long-Term damage
Knowledge-focused Recruiting nowThis study follows 300 people who had hospital-acquired pneumonia to see how it affects their heart and lungs over 18 months. Researchers will take blood samples, swabs, and perform heart and lung tests to understand the link between pneumonia and later cardiovascular problems li…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Massive brazilian registry aims to uncover hidden health risks in HIV patients
Knowledge-focused Recruiting nowThis study is creating a large database of health information from 743 adults with HIV/AIDS across Brazil. Researchers will look at how common chronic diseases like heart disease, kidney disease, and cancer are in this group. The goal is to gather data to help improve health poli…
Sponsor: Hospital Alemão Oswaldo Cruz • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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300,000 people get chest X-Rays in massive screening trial
Knowledge-focused Recruiting nowThis study is checking if chest X-rays can reliably find lung, heart, and esophagus problems in 300,000 adults during routine check-ups. People getting a health exam will have a chest X-ray, and if something looks off, they'll get a more detailed scan to confirm. The goal is to s…
Sponsor: Chinese Academy of Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Can a simple breath test diagnose diseases in children?
Knowledge-focused Recruiting nowThis study aims to see if analyzing the chemicals in a child's breath can help diagnose and monitor diseases like asthma, neurological disorders, and type 1 diabetes. Researchers will collect breath samples from up to 3,600 children and teens to find patterns linked to these cond…
Sponsor: University Children's Hospital Basel • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Could a simple device let bystanders save lives in breathing emergencies?
Knowledge-focused Recruiting nowThis study tests a new portable CPAP device designed to help people with sudden breathing failure before they reach the hospital. Researchers want to see if the device is easy enough for non-medical people to use correctly. The study involves 50 participants: healthy older adults…
Sponsor: Università Vita-Salute San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Scientists test how day vs. night heat changes your health
Knowledge-focused Recruiting nowThis study looks at how being in hot conditions during the day, at night, or both affects the body and mind. Thirty-five healthy adults aged 18-30 will spend time in a temperature-controlled room. Researchers will measure heart function, lung capacity, blood markers of inflammati…
Sponsor: Jian Cheng • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Morning or afternoon? study tests best time for COPD exercise
Knowledge-focused Recruiting nowThis study looks at whether doing exercise training in the morning or afternoon makes a difference for people with COPD. Researchers will measure walking distance, endurance, and balance in 90 patients. The goal is to see if matching exercise time to the body's natural clock can …
Sponsor: Michaël RACODON • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Asthma study seeks to tailor rehab by type
Knowledge-focused Recruiting nowThis study looks at 60 adults aged 35-75 with allergic or eosinophilic asthma to see if their symptoms, breathing problems, and frailty levels differ. Researchers will measure lung function, breathlessness, fatigue, and quality of life. The goal is to help health professionals de…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New sticker could track your breathing and save lives
Knowledge-focused Recruiting nowThis study tests a small, sticky chest sensor called PneumoRator that measures breathing rate continuously. Researchers will put it on 50 adults before major surgery and compare its readings to standard hospital monitors. The goal is to see if the device is accurate and comfortab…
Sponsor: University Hospital Southampton NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New telehealth program aims to boost lung cancer screening in hispanic communities
Knowledge-focused Recruiting nowThis study tests a telehealth coaching program called TELESCOPE, designed to help Hispanic adults at high risk for lung cancer decide whether to get screened. The program includes a decision aid, smoking cessation support, and help navigating the screening process. Researchers wi…
Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Can a swab of Mom's fluids boost C-Section Babies' microbiome?
Knowledge-focused Recruiting nowThis early-phase trial tests whether it is safe and practical to swab the noses of C-section babies with maternal vaginal secretions. The goal is to see if this can modify the baby's respiratory microbiome. Twenty healthy newborns will be randomly assigned to receive either the v…
Early phase 1 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Glove tracks hand movements to teach bronchoscopy
Knowledge-focused Recruiting nowThis study gathers video and hand-movement data from 300 patients and up to 20 doctors during routine bronchoscopy procedures. Researchers aim to use this data to create machine learning models that could help train new doctors. No new treatments or drugs are involved, and patien…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:56 UTC