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Pneumonia's hidden heart risk: new study tracks Long-Term damage

NCT ID NCT06602934

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 300 people who had hospital-acquired pneumonia to see how it affects their heart and lungs over 18 months. Researchers will take blood samples, swabs, and perform heart and lung tests to understand the link between pneumonia and later cardiovascular problems like heart attacks or strokes. The goal is to identify who is most at risk and why.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal why pneumonia increases the risk of heart attacks and strokes, pointing to new ways to prevent these complications.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may take years to translate into practical medical advice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Group A (patients with acute cardiac disease) * Male or female * Hospitalized for acute coronary syndrome for less than 7 days. * Informed consent from the patient * Person insured under a health insurance scheme Group B (patients with chronic cardiovascular disease) * Male or female, * Undergoing coronary artery by-pass surgery * Hospitalized in intensive care unit for \&gt; 12 hours * Informed consent from the patient * Person insured under a health insurance scheme Group C (patients at risk of CVRD without chronic cardiovascular disease) * Male or female, * Familial high levels of cholesterol or triglycerides * With no personal history of CVRD, with a recent negative cardiac exercise test (last test inferior to 12 months) * Follow-up for lipid abnormalities at high risk of CVRD events * Informed consent from the patient * Person insured under a health insurance scheme Group D (patients with HAP) * Male or female * With one or more risk factors for CVD among: Age ≥ 65 years old Smoking, Abnormal lipidic levels, High blood pressure, Obesity, Diabetes mellitus, Chronic kidney disease * Cured from mechanically ventilated HAP during the current hospitalization * Informed consent from the patient or relatives * Person insured under a health insurance scheme Exclusion Criteria: * Groups A, B, C and D * Age \<80 years old * Immunosuppression pre-existing to the index hospitalisation, defined as lymphopenia; 500 elements/mm3, haematologic cancer, aplasia, chemotherapy/radiotherapy for cancer within 3 months prior to the inclusion, or anti-graft rejection drug. * Pregnant women, breastfeeding women. * Adults under guardianship or trusteeship. * Low probability of survival at day 28. o Groups A, B, C * Community-acquired pneumonia or Hospital-acquired pneumonia within the last year.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Angers University Hospital

    NOT_YET_RECRUITING

    Angers, France

  • Nantes University Hospital

    RECRUITING

    Nantes, France

  • Rennes University Hospital

    NOT_YET_RECRUITING

    Rennes, France

  • Rouen University Hospital

    NOT_YET_RECRUITING

    Rouen, France

  • Toulouse University Hospital

    NOT_YET_RECRUITING

    Toulouse, France

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