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Can exercise rebuild lungs damaged by dust?

NCT ID NCT07744334

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 04, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This trial tests whether aerobic exercise or resistance exercise can improve lung function in male quarry workers who have breathing problems from years of dust exposure. Participants will be randomly assigned to one of three groups: aerobic training, resistance training, or a control group receiving routine care and breathing exercises. Over eight weeks, researchers will measure lung function, exercise capacity, and quality of life to see which approach helps most.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Aerobic exercise training and resistance exercise training
What this could lead to
If effective, this could point toward a practical, drug-free way to improve breathing and quality of life in workers with occupational lung problems.
What could go wrong
The trial is small and short-term, so results may not apply broadly. Exercise may not reverse long-term lung damage, and benefits could be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 75 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 40 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male quarry workers. * The age range is between 30 and 40 years. * BMI values from 25 to 29.9 kg/m². * They work 5 to 6 times per weeks with mean exposure range (5-10 years) (Kumar et al., 2014). Exhibited chest manifestations (Respiratory symptoms) like cough, dyspnea, wheeze, and ventilatory impairment with significant reduction in (FEV1/FVC\<70% and/or FVC\<80% and reduce Peak Expiratory flow 25- 75% (PEF25-75%)(Abdelwahaab et al., 2025). * Clinically stable (no exacerbation in past 4-6 weeks). * Low levels of physical activity (using the International Physical Activity Questionnaire-Short Version) (The Arabic version of the questionnaire will be used). Exclusion criteria: * Patients with acute respiratory infections or recent exacerbation(4-6 weeks). * Asthmatic patient. * Chest cancer. * Musculoskeletal diseases and other disorders that could potentially impact the study's findings are excluded from the trial. * Other major lung diseases (e.g., TB, ILD, bronchiectasis, cancer). * Unstable cardiovascular disease. * Uncontrolled hypertension. * Severe musculoskeletal or neurological limitation to exercise. * Cognitive impairment. * Participation in PR in past 6 months. * Heavy smokers.

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Conditions

The condition(s) this trial relates to.

occupational lung disease Respiration Disorders respiratory system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Occupational lung diseases Respiratory disorders Ventilatory defect

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Physical Therapy, Deraya University

    RECRUITING

    Minya, Minya Governorate, Egypt

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