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AI reads chest X-Rays in the ER to catch silent killers early

NCT ID NCT07391280

Diagnosis Sponsor: NHS Greater Glasgow and Clyde Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an AI program can help emergency doctors find undiagnosed heart failure, COPD, and cancer by analyzing chest X-rays. Researchers will compare diagnosis rates when doctors have access to the AI's findings versus when they don't. The trial involves 17,000 adults in one hospital's emergency department.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Harrison.ai Chest X-Ray Solution (AI software)
What this could lead to
If successful, this AI tool could help emergency doctors catch serious heart and lung diseases earlier, potentially improving treatment and outcomes.
What could go wrong
This is a large but early-stage study testing a new AI tool. It may not improve diagnosis rates, and the AI could miss or misread findings, leading to false alarms or missed cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 17,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Unconsented Use of Harrison CXR Algorithm in Emergency Department (ED): * Frontal Chest X-Ray (CXR) (AP or PA) acquired in the Queen Elizabeth University Hospital (QEUH) ED * Patients aged 18 or over * Appropriate meta data (DICOM) to allow for Harrison CXR processing and secondary capture report provision. Patient Focus Groups: * Aged 18 or over * Able to provide written, informed consent in English. Clinician Focus Groups: * Aged 18 or over * Able to provide written, informed consent in English. * Working as a doctor, advanced nurse practitioner or advanced clinical practitioner in ED, radiology or downstream medical specialties * For post-implementation focus groups only, must have at least 4 months experience of working with Harrison CXR algorithm. Diagnostic Clinic: * Patients without terminal illness or advanced frailty * Usual healthcare provider based in NHS GGC Exclusion Criteria: Applies to use of unconsented CXRs: \- Patient has requested that they are removed from the study, or has objected to the use of AI in their routine clinical care and this has been subsequently upheld by the health board. Applies to invitation to combined diagnostic clinic: * Patients not available to follow up, including patients i.e. whose the patient's usual care (or onward care following index admission) is out-with NHS GGC. * Patients who have been referred to palliative care for end-stage disease, or patients with severe frailty (i.e. bedbound) will not be invited to the combined diagnostic clinic For Patient and Clinician Focus Groups: * Unable to provide informed written consent in English * Aged \<18

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Conditions

The condition(s) this trial relates to.

cancer cardiovascular disorder chronic obstructive pulmonary disease heart failure lung neoplasm neoplasm respiratory system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Cardiovascular Respiratory

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Queen Elizabeth University Hospital

    RECRUITING

    Glasgow, United Kingdom

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Other studies related to the condition(s) this trial covers.