Lymphedema

This study looked at how well a robotic system called Symani helps surgeons perform very precise reconstructive surgeries on small blood vessels, lymph vessels, and nerves. It included 427 adults who needed this type of surgery after cancer, injury, birth defects, or for lymphede…

This study tested a daily pill called acebilustat in 40 adults with long-term arm lymphedema (stage 2, lasting over 6 months). Participants took either the drug or a placebo for 9 months, with the first 3 months on placebo for all. The main goal was to see if the drug reduces ski…

This study looked at whether adding a special type of physiotherapy after lymphovenous anastomosis surgery helps people with lymphedema more than physiotherapy alone. Lymphedema is a condition where fluid builds up and causes swelling, often after cancer treatment. The study invo…

This study looked at whether adding a device that applies gentle suction (negative pressure) to standard lymphedema therapy helps reduce arm swelling in women who developed lymphedema after cancer treatment. Eighteen participants received both standard therapy and the combined ap…

This study tested new adhesive sensors that stick to the skin to see if they can detect early signs of lymphedema, a painful arm swelling that can happen after cancer treatment. Researchers compared readings from 76 people with and without lymphedema. The goal is to create a simp…

This study tested small wearable sensors to see if they can accurately measure lymphedema, a condition where fluid builds up and causes swelling, often after cancer treatment. Thirty adults with arm lymphedema wore the sensors during one visit, and researchers compared the readin…

This study tested a device called Insight Pro to see if it can safely detect lymphatic and vein disorders, such as lymphedema and chronic venous insufficiency. The device measures fluid buildup and skin hardness in the arms or legs. A total of 67 adults with or without these cond…

This study looked at whether adding physical therapy to educational materials could prevent lymphedema (arm swelling) in women treated for breast cancer. Over 1,000 women who had lymph nodes removed were randomly assigned to receive either education alone or education plus a pers…

This trial tests whether a self-management program can reduce lymphedema symptoms and improve quality of life in women with breast cancer who have developed arm swelling after mastectomy. Participants will learn exercises and receive education on lymphedema care, such as skin pro…

This study tests if progressive resistance exercise can improve arm swelling and function in people who developed lymphedema after breast cancer treatment. Fifty adults aged 18-60 who are at least 3 months past surgery will be enrolled. Participants will do supervised exercises a…

This study looked at whether closed kinetic chain and weight shifting exercises can improve balance and stability in women who have arm swelling (lymphedema) after a mastectomy. Sixty women aged 40-60 with moderate lymphedema participated. They did exercises designed to strengthe…

This study tests whether adding aerobic exercise to standard lymphedema therapy (complex decongestive physiotherapy) can improve walking, balance, leg strength, and daily function. Twenty-four adults with bilateral lower limb lymphedema will be randomly assigned to either standar…

This trial investigates whether a supervised program of aerobic and strength exercises can improve or prevent lymphedema—a painful arm swelling—in women who have had breast cancer treatment. Participants are assigned to either an exercise group or a no-exercise control group. Res…

This study tested a new, standardized process for providing assistive devices (like special tools) to help people put on and take off compression stockings. 220 adults who need these stockings long-term took part. The goal was to see if the new method improves how often people us…

This study looked at whether adding a machine called LPG Cellu M6 to standard treatment helps reduce arm swelling (lymphedema) in breast cancer patients. About 93 people with moderate to severe swelling for at least 6 months took part. The goal was to see if more patients could r…

This study tested whether a special nursing plan (called ERAS) could help women recover after surgery for cervical cancer. 160 women were split into two groups: one got the ERAS nursing plan, the other got standard care. The goal was to see if the ERAS plan could lower the risk o…

This study tested two non-drug treatments—kinesio taping and low-level laser therapy—on 66 women with arm swelling (lymphedema) after mastectomy for stage II breast cancer. The goal was to see which method better reduced arm size, improved hand grip strength, and eased shoulder p…

This study looked at whether adding manual lymph drainage to standard compression therapy improves outcomes for people with lower leg lymphedema. Thirty-one participants were randomly assigned to receive either compression alone or compression plus manual lymph drainage. The rese…

This study looked at whether adding TECAR therapy or shock wave therapy to standard treatment (complex decongestive therapy) could better reduce leg swelling in severely obese women with lymphedema. Forty-five women took part, receiving one of three treatments over four weeks. Re…

This study tested whether an advanced pneumatic compression device (Flexitouch Plus) could reduce swelling and symptoms in 236 head and neck cancer survivors with lymphedema. Participants either used the device daily or received usual care like manual drainage and compression gar…

This study tested a wearable compression device called Dayspring for people with lymphedema in one leg. 24 adults used the device daily for 3 months. Researchers measured changes in leg swelling and quality of life to see if the device was safe and helpful.

This study looked at breast reconstruction using only a patient's own fat (lipomodulin) after mastectomy for breast cancer. Researchers wanted to see how often the procedure works, how the breast looks afterward, and how it affects quality of life. The study included 118 women wh…

This study looked at whether a home-based exercise program can help people with head and neck cancer maintain movement, muscle strength, and posture while undergoing radiation therapy. Twenty-four adults who had surgery and were scheduled for radiation took part. The goal was to …

This study tested a new vibrating device called LymphaVibe for treating arm lymphedema, a painful swelling from fluid buildup. Fifteen adults with lymphedema used the device for 40 minutes during a clinic visit. Researchers measured arm size, pain, and side effects before and aft…

This pilot study tested whether a 12-week program of special exercises combined with advanced compression garments could reduce arm swelling in breast cancer survivors with lymphedema. Sixty women with mild to moderate chronic lymphedema were enrolled. The goal was to see if the …

This study tested a new portable, non-pneumatic compression device (Dayspring) against a standard pneumatic compression device for treating leg lymphedema. 121 adults with leg swelling used each device for three months, with a month off in between. Researchers measured changes in…

This study compared a new wearable compression device (Dayspring) to a standard pneumatic pump for treating arm swelling caused by breast cancer treatment. Fifty adults with lymphedema used both devices in a crossover design. Researchers measured arm volume changes and quality of…

This study looked at whether starting a personalized exercise program before breast cancer surgery helps women recover better. Thirty female survivors followed the program for 12 months. The goal was to improve shoulder motion, reduce pain, and enhance daily function and quality …

This study tested a treatment called Complex Decongestive Therapy (CDT) for people with venous insufficiency, a condition where leg veins struggle to send blood back to the heart. Twenty-one adults received either CDT plus exercises or exercises alone. The goal was to see if CDT …

This study tested whether adding underwater electrical stimulation to standard therapy helps women with arm swelling after mastectomy. Sixty women received either standard therapy alone or standard therapy plus the electrical bath. The goal was to see if the combination reduced p…

This pilot study tested whether low-energy shock wave therapy can help people with axillary web syndrome, a common complication after breast cancer surgery that causes painful, tight cords under the arm. Twenty patients received four weekly sessions of shock waves to the affected…

This study looks at whether women with lymphedema in one leg have worse balance and body awareness compared to healthy women. Lymphedema causes swelling due to fluid buildup, which may make the limb feel heavy and affect how the body senses and controls movement. Researchers will…

This study looked at whether nerve signals (called sympathetic skin response) are linked to how well women respond to standard lymphedema therapy after breast cancer surgery. Thirty women with lymphedema and thirty healthy women had nerve tests and filled out symptom questionnair…

This study tested whether focused questionnaires can detect lymphedema—a common complication after armpit lymph node removal—earlier than physical measurements like arm circumference. Researchers followed 101 breast cancer patients who had or were scheduled for axillary dissectio…

This study tested a mobile 3D scanning app to measure swelling (lymphedema) in the head and neck area. Lymphedema is a buildup of fluid that causes swelling, often after cancer treatment. The goal was to see if this simple scanning method could accurately measure swelling and tra…

This study looked at how breast cancer-related lymphedema (arm swelling) affects the way women walk. Researchers compared 40 women with lymphedema to healthy volunteers, measuring arm swelling, shoulder movement, grip strength, and walking patterns. The goal was to understand if …

This study looked at whether chemotherapy before breast cancer surgery causes extra fluid buildup in the arm, an early sign of lymphedema. Researchers measured 111 women's arm fluid before and after chemo using a special device. The goal was to understand how often this happens a…

This study looked at 1,000 women who had breast reconstruction with implants right after mastectomy, followed by radiation therapy. Researchers compared two types of implants—polyurethane-covered and non-polyurethane-covered—to see which had fewer complications like capsular cont…

This study tested a new ultrasound device to measure skin stiffness (fibrosis) in people with lymphedema or venous insufficiency. Researchers compared results from 130 participants, including healthy volunteers, to see if the device could detect differences in skin hardness. The …

This study tested a new sensor (CIMON) to see if it can accurately measure how well compression bandages reduce leg swelling in people with chronic edema (long-term fluid buildup). Fifty-two adults with leg swelling who needed compression bandages took part. The sensor was placed…

This completed study looked at 133 breast cancer patients to develop a way to predict who will get arm swelling (lymphedema) after lymph node removal surgery. Researchers examined patient characteristics, proteins, and genes to build a risk model. The goal is to help doctors iden…

This study looked at 111 people who had surgery for early-stage cervical or vulvar cancer to find out how many develop lower leg swelling (lymphedema). Researchers used a questionnaire to gather information, not to test any new treatment. The goal is to better identify who is at …

This study looked back at medical records of 172 people with lymphedema to compare two treatments: a device called LymphaTouch and manual lymphatic drainage (a type of massage). The goal was to see which one better reduced arm or leg swelling. Researchers measured limb size befor…

This study looked at a questionnaire designed to measure how leg swelling (lymphedema) affects daily life. Researchers tested a French version for accuracy and checked if the Dutch version can track changes over time. Over 450 people with leg lymphedema filled out the questionnai…

This study looked at 50 people with head and neck cancer to see how often swelling (lymphedema) happens after treatment. Researchers measured fluid levels in the head and neck before and after cancer therapy and checked quality of life. The goal was to better understand the probl…

This completed observational study looked at 110 breast cancer patients to see if arm swelling (lymphedema) is linked to a specific type of muscle pain called myofascial pain syndrome. Researchers examined trigger points in key muscles and measured pain thresholds. The goal was t…