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Leg swelling relief: simple therapy shows promise for vein disease

NCT ID NCT06231940

Symptom relief Sponsor: University of Salamanca Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a treatment called Complex Decongestive Therapy (CDT) for people with venous insufficiency, a condition where leg veins struggle to send blood back to the heart. Twenty-one adults received either CDT plus exercises or exercises alone. The goal was to see if CDT could improve vein flow and reduce swelling. The study is complete, but results are not yet widely available.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Complex Decongestive Therapy (CDT) - a treatment involving manual lymph drainage, compression, and exercises to reduce swelling
What this could lead to
If it works, this could offer a non-drug way to ease swelling and discomfort in people with vein problems.
What could go wrong
This is a very small, completed study with only 21 participants. Results may not apply to everyone, and the treatment requires ongoing effort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

21 people

The number who actually took part.

Started

Oct 2022

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 35 and 75 years * Presence of mild venous insufficiency, moderate or severe (grades C1, C2, C3, and C4 on the Clinical, Etiologic, Anatomic, Pathophysiologic \[CEAP\] scale). Exclusion Criteria: * Subjects affected by uncompensated acute cardiac, hepatic, and renal disease, acute obstructive vascular disease, acute trauma, primary lymphedema, and acute skin infections. * Patients who are currently receiving complex decongestive therapy treatment or in the last six months.

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Conditions

The condition(s) this trial relates to.

cellulitis lymphedema vein disorder venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cellulitis of leg Lymphatic edema Vein disease

Contacts and locations

Locations

  • Beatriz María Bermejo Gil

    Salamanca, Salamanca, 37007, Spain

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