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Can we shorten antibiotic treatment for cellulitis? new study seeks answers

NCT ID NCT05023200

Knowledge-focused Sponsor: University of Sussex Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

Cellulitis is a painful skin infection that often requires antibiotics, but the ideal treatment length is unknown. This study followed 230 adults hospitalized with cellulitis to identify factors that predict a good recovery, such as medical history and early response to treatment. The goal is to develop rules that help doctors prescribe the right amount of antibiotics for each patient, avoiding unnecessary use and reducing risks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to personalized antibiotic treatment rules for cellulitis, reducing unnecessary antibiotic use and side effects.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test a new drug or cure. The findings may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

230 people

The number who actually took part.

Started

Jun 2021

Finished

Sep 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Hospital-based or services delivering antibiotic treatment and ongoing follow-up regardless of location.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (age ≥18 years) identified by their treating clinician as having lower limb cellulitis that requires IV or oral antibiotic treatment either from the hospital or another service based outside of the hospital, which will conduct ongoing follow-up regardless of location. Exclusion Criteria: Patients: * who have already received 3 or more calendar days of antibiotics from the hospital for cellulitis. * receiving antibiotic therapy for another indication that is anticipated to continue for longer than the antibiotic treatment for cellulitis and that, in the judgement of the investigator, would impact the study assessments. * for whom a surgical procedure to treat their cellulitis is planned (i.e. debridement of suspected necrotising skin / soft tissue infection). * who, in the judgement of the investigator, do not have a clear diagnosis of cellulitis (to enable the exclusion of infections, such as severe/deep diabetic foot infection, which may be loosely labelled as cellulitis, but treated with different guideline antibiotic agents and durations). * lack capacity to give informed consent to participate. * are receiving end-of-life care. * are already involved in a CTIMP of relevance to the treatment of their cellulitis. * are unlikely, in the opinion of the investigator, to comply with study procedures.

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Conditions

The condition(s) this trial relates to.

cellulitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Antibiotic duration Cellulitis Cellulitis of leg

Contacts and locations

Locations

  • University Hospitals Sussex NHS Foundation Trust

    Brighton, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.