Kidney disorder
MONDO:0005240A disease involving the kidney.
Also known as: disease of kidney, disease or disorder of kidney, disorder of kidney, kidney disease, kidney disease or disorder, kidney disorder, renal disease, renal disorder
4039 clinical trials for this condition and its sub-types, 223 tagged with Kidney disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Kidney disorder
-
Chronic kidney disease 1,096 trials · 1,571 incl. sub-types
6 sub-types
- Chronic renal failure syndrome 835 trials
- End stage renal failure 691 trials
- Diabetic kidney disease 133 trials
- Chronic pyelonephritis 1 trial Sub-types →
- Chronic rapidly progressive glomerulonephritis 1 trial
- Arterionephrosclerosis 0 trials
-
Kidney failure 236 trials · 1,393 incl. sub-types
3 sub-types
- Chronic renal failure syndrome 835 trials
- Acute kidney injury 415 trials Sub-types →
- Uremia 16 trials Sub-types →
-
Kidney neoplasm 59 trials · 860 incl. sub-types
8 sub-types
- Kidney cancer 244 trials · 851 incl. sub-types Sub-types →
- Childhood kidney neoplasm 1 trial · 30 incl. sub-types Sub-types →
- Renal pelvis neoplasm 1 trial · 24 incl. sub-types Sub-types →
- Kidney benign neoplasm 4 trials · 12 incl. sub-types Sub-types →
- Mesonephric neoplasm 1 trial · 3 incl. sub-types Sub-types →
- Kidney hemangiopericytoma 0 trials
- Mixed epithelial stromal tumor of the kidney 0 trials Sub-types →
- Multiloculated renal cyst 0 trials
-
Nephritis 16 trials · 504 incl. sub-types
4 sub-types
- Glomerulonephritis 33 trials · 457 incl. sub-types Sub-types →
- Hereditary nephritis 17 trials · 152 incl. sub-types Sub-types →
- Pyelitis 0 trials · 21 incl. sub-types Sub-types →
- Interstitial nephritis 6 trials · 9 incl. sub-types Sub-types →
-
Glomerular disorder 9 trials · 482 incl. sub-types
6 sub-types
- Glomerulonephritis 33 trials · 457 incl. sub-types Sub-types →
- Glomerulosclerosis 1 trial · 51 incl. sub-types Sub-types →
- Immunotactoid or fibrillary glomerulopathy 0 trials · 1 incl. sub-types Sub-types →
- Collagen type III glomerulopathy 0 trials
- Congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization 0 trials
- Fibronectin glomerulopathy 0 trials Sub-types →
-
Inherited kidney disorder 1 trial · 317 incl. sub-types
26 sub-types
- Hereditary nephritis 17 trials · 152 incl. sub-types Sub-types →
- Familial cystic renal disease 0 trials · 72 incl. sub-types Sub-types →
- Inherited renal tubular disease 0 trials · 40 incl. sub-types Sub-types →
- Familial nephrotic syndrome 0 trials · 22 incl. sub-types Sub-types →
- Congenital anomaly of kidney and urinary tract 7 trials · 14 incl. sub-types Sub-types →
- Nephrolithiasis, calcium oxalate 13 trials Sub-types →
- Neurohypophyseal diabetes insipidus 9 trials
- Hereditary renal cell carcinoma 1 trial · 7 incl. sub-types Sub-types →
- Inherited focal segmental glomerulosclerosis 1 trial · 4 incl. sub-types Sub-types →
- Inherited pseudohypoaldosteronism 0 trials · 4 incl. sub-types Sub-types →
- Renal agenesis 1 trial · 2 incl. sub-types Sub-types →
- Liddle syndrome 1 trial Sub-types →
- Hereditary kidney oncocytoma 1 trial
- Prune belly syndrome 1 trial
- Alsing syndrome 0 trials
- Gitelman-like kidney tubulopathy due to mitochondrial DNA mutation 0 trials
- Familial juvenile hyperuricemic nephropathy 0 trials Sub-types →
- Familial renal glucosuria 0 trials
- Fibronectin glomerulopathy 0 trials Sub-types →
- Hypophosphatemic nephrolithiasis/osteoporosis 1 0 trials
- Hypophosphatemic nephrolithiasis/osteoporosis 2 0 trials
- Inherited distal renal tubular acidosis 0 trials Sub-types →
- Nail-patella-like renal disease 0 trials
- Nephrolithiasis, X-linked recessive, with renal failure 0 trials
- Proteinuria, low molecular weight, with hypercalciuria and nephrocalcinosis 0 trials
- Renal tubular dysgenesis of genetic origin 0 trials Sub-types →
-
Nephrolithiasis 252 trials · 254 incl. sub-types
3 sub-types
- Nephrolithiasis, calcium oxalate 13 trials Sub-types →
- Acute urate nephropathy 4 trials
- Nephrolithiasis, X-linked recessive, with renal failure 0 trials
-
Proteinuria 66 trials · 138 incl. sub-types
2 sub-types
- Hemoglobinuria 1 trial · 73 incl. sub-types Sub-types →
- Proteinuria, low molecular weight, with hypercalciuria and nephrocalcinosis 0 trials
-
Impaired renal function disease 109 trials · 129 incl. sub-types
4 sub-types
- Secondary hyperparathyroidism of renal origin 7 trials · 18 incl. sub-types Sub-types →
- Nephrogenic diabetes insipidus 1 trial · 2 incl. sub-types Sub-types →
- Hypophosphatemic nephrolithiasis/osteoporosis 1 0 trials
- Hypophosphatemic nephrolithiasis/osteoporosis 2 0 trials
-
Cystic kidney disease 8 trials · 87 incl. sub-types
4 sub-types
- Familial cystic renal disease 0 trials · 72 incl. sub-types Sub-types →
- Multicystic dysplastic kidney 1 trial · 10 incl. sub-types Sub-types →
- Medullary sponge kidney 1 trial
- Non-congenital cyst of kidney 0 trials
-
Nephrosis 0 trials · 71 incl. sub-types
1 sub-type
- Nephrotic syndrome 47 trials · 71 incl. sub-types Sub-types →
-
Renal infectious disease 16 trials · 64 incl. sub-types
4 sub-types
- Hantavirus hemorrhagic fever with renal syndrome 5 trials · 37 incl. sub-types Sub-types →
- Pyelonephritis 8 trials · 21 incl. sub-types Sub-types →
- Adenovirus renal infection 0 trials
- Renal tuberculosis 0 trials
-
Renal tubule disorder 1 trial · 47 incl. sub-types
4 sub-types
- Inherited renal tubular disease 0 trials · 40 incl. sub-types Sub-types →
- Fanconi renotubular syndrome 4 trials Sub-types →
- Renal tubular acidosis 2 trials Sub-types →
- Mucinous tubular and spindle renal cell carcinoma 0 trials
-
Diabetes insipidus 34 trials · 38 incl. sub-types
4 sub-types
- Neurohypophyseal diabetes insipidus 9 trials
- Nephrogenic diabetes insipidus 1 trial · 2 incl. sub-types Sub-types →
- Dipsogenic diabetes insipidus 0 trials
- Gestational diabetes insipidus 0 trials
-
Renal tubular transport disease 0 trials · 17 incl. sub-types
9 sub-types
- Dent disease 5 trials Sub-types →
- Pseudohypoaldosteronism 3 trials · 5 incl. sub-types Sub-types →
- Fanconi renotubular syndrome 4 trials Sub-types →
- Renal tubular acidosis 2 trials Sub-types →
- Liddle syndrome 1 trial Sub-types →
- Renal hypomagnesemia 3 1 trial
- Bartter syndrome 0 trials Sub-types →
- Gitelman syndrome 0 trials
- Familial renal glucosuria 0 trials
-
Stricture or kinking of ureter 9 trials
-
Hydronephrosis 7 trials · 9 incl. sub-types
1 sub-type
- Congenital hydronephrosis 3 trials
-
Hypertensive nephropathy 8 trials
2 sub-types
- Benign hypertensive renal disease 0 trials
- Malignant hypertensive renal disease 0 trials Sub-types →
-
Nephrocalcinosis 7 trials · 8 incl. sub-types
1 sub-type
- Renal hypomagnesemia 3 1 trial
-
Renal artery disease 3 trials · 7 incl. sub-types
3 sub-types
- Renal artery atheroma 4 trials
- Renal artery obstruction 3 trials
- Nephrosclerosis 0 trials
-
Fetal lower urinary tract obstruction 0 trials · 6 incl. sub-types
5 sub-types
- Posterior urethral valve 5 trials
- Prune belly syndrome 1 trial
- Anterior urethral valve 0 trials
- Atresia of urethra 0 trials
- Urethral obstruction sequence 0 trials
-
Congenital primary megaureter 5 trials
5 sub-types
- Congenital primary megaureter, nonrefluxing and unobstructed form 0 trials
- Congenital primary megaureter, obstructed form 0 trials
- Congenital primary megaureter, refluxing and obstructed form 0 trials
- Congenital primary megaureter, refluxing form 0 trials
- Primary megaureter, adult-onset form 0 trials
-
Renal hypertension 0 trials · 4 incl. sub-types
3 sub-types
- Renovascular hypertension 4 trials
- Benign renovascular hypertension 0 trials
- Malignant renovascular hypertension 0 trials
-
Distal renal tubular acidosis 3 trials
2 sub-types
-
Exstrophy-epispadias complex 1 trial · 3 incl. sub-types
4 sub-types
- Bladder exstrophy 3 trials
- Bladder exstrophy-epispadias-cloacal extrophy complex 1 trial
- Cloacal exstrophy 0 trials
- Epispadias 0 trials
-
Acute tubulointerstitial nephritis 2 trials
-
Kidney cortex necrosis 2 trials
-
IgG4-related kidney disease 1 trial
-
Anuria 1 trial
-
Crush syndrome 1 trial
-
Obstructive nephropathy 1 trial
-
Orthostatic proteinuria 1 trial
-
Renal hypoplasia 1 trial
2 sub-types
- Renal hypoplasia, bilateral 0 trials
- Renal hypoplasia, unilateral 0 trials
-
Renal nutcracker syndrome 1 trial
-
Arnold stickler bourne syndrome 0 trials
-
C1q nephropathy 0 trials
-
1 sub-type
- Leiomyoma of vulva and esophagus 0 trials
-
Atheroembolism of kidney 0 trials
-
Congenital megacalycosis 0 trials
2 sub-types
- Congenital bilateral megacalycosis 0 trials
- Unilateral congenital megacalycosis 0 trials
-
Congenital renal artery stenosis 0 trials
-
Duplication of urethra 0 trials
-
Kidney cortex disease 0 trials
-
Kidney hypertrophy 0 trials
-
Kidney papillary necrosis 0 trials
1 sub-type
- Acute papillary necrosis 0 trials
-
Lachiewicz sibley syndrome 0 trials
-
Neonatal renal venous thrombosis 0 trials
-
Non-syndromic supernumerary kidneys 0 trials
-
Oligomeganephronia 0 trials
-
Perinephritis 0 trials
-
Pyonephrosis 0 trials
-
Renal aminoaciduria 0 trials
-
Renal dysplasia 0 trials
2 sub-types
- Renal dysplasia, bilateral 0 trials
- Renal dysplasia, unilateral 0 trials
-
Renal tubular dysgenesis 0 trials
3 sub-types
Most studied deeper sub-types
-
New drug cocktail aims to protect kidneys in High-Risk patients
Disease control OngoingThis Phase 2 study tests whether a combination of two drugs, zibotentan and dapagliflozin, works better than dapagliflozin alone at reducing protein leakage in urine for adults with chronic kidney disease. About 224 participants will receive either the combo or the single drug. T…
Phase 2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
-
Can digital tools and training help more kidney patients get transplants?
Disease control OngoingThis trial tests a comprehensive approach to improve kidney care and increase transplant rates. It combines provider training, digital dashboards, and a mobile health app to educate patients and help them find living donors. The study includes 5,000 adults with advanced chronic k…
Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
-
Could a blood pressure pill shield blood vessels from heart attacks?
Disease control OngoingThis trial tests whether sparsentan, a tablet that blocks a chemical called endothelin and lowers blood pressure, can improve blood vessel function and reduce stiffness in people with ANCA-associated vasculitis. Vasculitis is an autoimmune disease that damages blood vessels and r…
Phase 2 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
-
Could a new drug shield hearts and kidneys in overweight people?
Disease control OngoingThis phase 3 trial is testing whether the drug retatrutide can lower the chance of serious heart problems (like heart attacks and strokes) and slow kidney disease in 10,000 overweight adults who already have heart or kidney disease. Participants receive either retatrutide or a pl…
Phase 3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
-
New pill combo aims to slow kidney decline in High-Risk patients
Disease control OngoingThis Phase 3 trial tests whether adding zibotentan to the standard drug dapagliflozin can better protect kidney function in people with chronic kidney disease and high proteinuria. About 1,800 adults are taking either the combo or dapagliflozin alone. The main goal is to see if t…
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
-
Experimental drug GSK4771261 takes first step against inherited kidney disease
Disease control OngoingThis study tests an experimental drug called GSK4771261 for safety and how the body processes it. Part A involves healthy volunteers, and Part B includes people with autosomal dominant polycystic kidney disease (ADPKD), a genetic condition that causes kidney cysts and can lead to…
Phase 1 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
-
Can an Anti-Inflammatory diet protect the kidneys? a trial puts the autoimmune protocol to the test
Disease control CancelledThis UCLA study is testing whether the Autoimmune Protocol (AIP) diet — which avoids dairy, grains, and sugar — can reduce protein levels in the urine of people with IgA nephropathy, a kidney disease that can lead to kidney failure. Thirty adults aged 18 to 65 with active disease…
Sponsor: University of California, Los Angeles • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
-
New weekly shot could help diabetics with kidney trouble control blood sugar
Disease control OngoingThis study tests a once-weekly injection called retatrutide in 320 adults with type 2 diabetes and moderate to severe kidney disease who are not controlling their blood sugar well on insulin. Participants will receive either the drug or a placebo for about 14 months. The goal is …
Phase 3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
-
New hope for rare kidney cancer: targeted drug savolitinib faces off against standard therapy
Disease control OngoingThis phase 3 study compares a new drug, savolitinib, to the standard drug sunitinib in 60 people with a specific type of advanced kidney cancer called MET-driven papillary renal cell carcinoma. The goal is to see if savolitinib is better at stopping the cancer from growing and to…
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
-
New hope for fabry patients with kidney failure: drug dosing study underway
Disease control OngoingThis study tests the safety and how the body processes migalastat in 14 adults with Fabry disease who have severe kidney impairment or are on dialysis. Participants take migalastat capsules, and researchers measure drug levels in blood and dialysate. The goal is to ensure proper …
Phase 3 • Sponsor: Amicus Therapeutics • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
-
New hope for transplant patients: drug targets kidney protein leak
Disease control OngoingThis study tests a drug called sparsentan for people who have protein in their urine after a kidney transplant due to IgA nephropathy or FSGS. About 20 adults will take the drug once daily for 36 weeks to see if it safely reduces protein levels and protects kidney function. The g…
Phase 4 • Sponsor: Travere Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
-
New drug aims to slow kidney failure in common kidney disease
Disease control OngoingThis phase 3 trial tests whether the drug atrasentan can slow kidney function loss in people with IgA nephropathy, a disease that can lead to kidney failure. About 404 participants receive either atrasentan or a placebo, along with standard care. The main goal is to see if atrase…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
-
Supplement shows promise for kidney Patients' heart health
Disease control OngoingThis study tests whether a natural supplement called nicotinamide riboside can improve artery stiffness and lower blood pressure in people with moderate to severe chronic kidney disease. About 118 adults aged 35-80 will take either the supplement or a placebo for 3 months. The go…
Phase 2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
-
Kidney transplant virus filter trial pulled before start
Disease control CancelledThis study aimed to see if a special blood filter (Seraph 100) could reduce BK virus levels in kidney transplant patients with high viral loads. It planned to enroll adults with a BK virus level of 10,000 IU/mL or higher who already had dialysis access. However, the trial was wit…
Sponsor: ExThera Medical Europe BV • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
-
Simple dialysis tweak could save thousands of lives
Disease control OngoingThis study looks at whether adding more magnesium to the fluid used during dialysis can help people with kidney failure live longer and have fewer heart-related hospital stays. Many dialysis patients have low magnesium, which can lead to muscle cramps and heart issues. The trial …
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
-
New hope for kidney disease patients: finerenone trial aims to reduce protein leakage
Disease control By invitation onlyThis study tests whether the drug finerenone can lower protein levels in the urine of people with chronic kidney disease who are not taking certain blood pressure medications. About 180 adults will receive either finerenone or a placebo for 6 months. The goal is to see if fineren…
Phase 3 • Sponsor: University Medical Center Groningen • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
-
Plant-Based diet trial aims to cut kidney transplant complications
Disease control OngoingThis study tests whether teaching kidney transplant recipients to eat a whole-food plant-based diet can improve their blood pressure, blood sugar, and weight, and reduce hospital visits and infections. About 49 adults who had a kidney transplant in the past 2–12 months and have h…
Sponsor: University of California, Davis • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
-
Sickle cell kidney trial pulled before it began
Disease control CancelledThis study aimed to see if the drug mitapivat could help people with sickle cell disease who also have kidney damage. It planned to measure changes in a key kidney marker over six months. However, the trial was withdrawn before enrolling any participants, so no results are availa…
Phase 2 • Sponsor: Agios Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
-
New shot shows promise in slowing kidney disease
Disease control OngoingThis phase 3 study tests BION-1301 (Zigakibart) in 383 adults with IgA nephropathy, a kidney disease that can lead to kidney failure. Participants receive either the drug or a placebo as a shot every 2 weeks for 2 years. The main goal is to see if the drug helps preserve kidney f…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
-
Can a common supplement shield dialysis Kids' hearts?
Disease control By invitation onlyThis study tests whether a daily dose of alpha lipoic acid, an antioxidant supplement, can lower the risk of heart problems in 50 children who are on regular hemodialysis. Participants will either take the supplement or a placebo pill for a period, and researchers will monitor fo…
Phase 3 • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
-
Kidney anemia pill for kids pulled before starting
Disease control CancelledThis study planned to test a daily pill called vadadustat for anemia in children with chronic kidney disease. It aimed to see if the pill could safely replace standard injections. However, the trial was withdrawn before enrolling any participants, so no results are available.
Phase 3 • Sponsor: Akebia Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
-
Kidney anemia pill study for kids pulled before it started
Disease control CancelledThis study was designed to test a once-daily pill called vadadustat for treating anemia in children with chronic kidney disease. The goal was to see if the drug could safely raise red blood cell levels without the need for injections. However, the study was withdrawn before enrol…
Phase 3 • Sponsor: Akebia Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
-
Could a diabetes drug shield Kids' kidneys?
Disease control OngoingThis study tests whether dapagliflozin, a drug used in adults for diabetes and kidney protection, can reduce protein leakage in the urine of children with chronic kidney disease. Ten children aged 4 to 18 with persistent proteinuria despite standard therapy will take the drug, an…
Sponsor: Al-Quds University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
-
Heart specialist Check-Ins could save lives in GP surgeries
Disease control OngoingThis study tests whether having extra appointments with a heart specialist at a local GP practice helps people get better treatment for heart, kidney, metabolic, and lung conditions. 138 high-risk adults will either receive standard GP care or additional specialist reviews to opt…
Sponsor: University of Leeds • Aim: Disease control
Last updated Jun 26, 2026 17:32 UTC
-
AI coach may soothe the agony of Dialysis-Related itching
Symptom relief OngoingThis study tests whether an artificial intelligence-supported education program can help reduce itching in people with chronic kidney disease who are on hemodialysis. The program teaches patients about causes of itching, skin care, diet, and self-management strategies through an …
Sponsor: Izmir Tinaztepe University • Aim: Symptom relief
Last updated Aug 02, 2026 00:00 UTC
-
New hope for kidney stone patients: safer pain relief after surgery?
Symptom relief OngoingThis study compares two drugs—methocarbamol and oxybutynin—to see which works better for pain and discomfort caused by a ureteral stent placed after kidney stone surgery. About 126 adults aged 18 to 80 who have the surgery will take one of the study drugs along with standard pain…
Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
-
Could your bone health decide if a dental implant lasts?
Knowledge-focused OngoingThis study looks back at dental implant cases to see if bone-related conditions—like vitamin D deficiency, calcium problems, or kidney disease—make implant failure more likely. Researchers will compare 192 failed implants with successful ones from similar patients. The goal is to…
Sponsor: University of Barcelona • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
-
Antidepressant doses under scrutiny for kidney patients
Knowledge-focused OngoingThis study examined whether starting a higher dose of two common antidepressants (venlafaxine and duloxetine) increases the risk of emergency visits, hospital stays, or death within 30 days in older adults with chronic kidney disease. Researchers analyzed health records from over…
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
-
Kidney patients needed to test how drug moves in body
Knowledge-focused OngoingThis study looks at how the drug eloralintide enters the bloodstream and leaves the body in people with severe kidney disease or kidney failure, compared to healthy volunteers. About 28 participants will receive a single shot under the skin. The study lasts about 14 weeks and doe…
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
-
Massive study reveals best Second-Line diabetes meds for heart and kidney protection
Knowledge-focused OngoingThis study looks at health records from over 780,000 people with type 2 diabetes to compare four common second-line medications: SGLT2 inhibitors, GLP-1 receptor agonists, DPP-4 inhibitors, and sulfonylureas. The goal is to see which drug class is most effective at preventing hea…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
-
Kidney Drug's hidden heart benefits under the microscope
Knowledge-focused OngoingThis study looks at how dapagliflozin, a diabetes drug, affects heart function and metabolism in people with chronic kidney disease. Researchers will measure heart strain, oxygen use during exercise, and blood chemicals in 60 adults. The goal is to understand how the drug works b…
Phase 1/2 • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
-
Hidden killers in controlled hypertension: study probes why blood pressure meds aren't enough
Knowledge-focused OngoingThis study combines data from over 2,500 people with treated and controlled high blood pressure to understand why some still die from heart attacks, strokes, or kidney failure. Researchers are looking beyond blood pressure numbers to find other factors that might predict these fa…
Sponsor: DejthidaNathaphong • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
-
Phone navigators aim to boost kidney donations
Knowledge-focused OngoingThis study tests whether a tele-health navigator program can help more kidney transplant candidates find living donors. About 347 adults with end-stage kidney disease will either get the navigator support or standard care. The goal is to see if remote guidance increases donor scr…
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
-
New study aims to close kidney transplant gap for minorities
Knowledge-focused OngoingHispanic/Latino and American Indian patients are less likely to get kidney transplants, even though they have higher rates of kidney failure. This study compares two methods to help them complete the transplant evaluation process: a fast-track evaluation done in one day or within…
Sponsor: University of New Mexico • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
-
Scientists hunt for genes behind kidney disease
Knowledge-focused OngoingThis study aims to find the genetic causes of kidney diseases like FSGS and nephrotic syndrome. Researchers will collect saliva and urine samples from up to 2,050 participants, including patients and their family members, as well as healthy volunteers. The goal is to understand w…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
-
Gene study aims to boost kidney transplant success for african americans
Knowledge-focused OngoingThe APOLLO study looks at how variations in the APOL1 gene, common in people of African ancestry, affect kidney transplant outcomes. Researchers are testing DNA from 5,000 kidney donors and recipients to see if certain gene variants lead to faster kidney failure or harm living do…
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
-
Kidney function may affect hepatitis b drug levels
Knowledge-focused OngoingThis study gives a single dose of bepirovirsen to 32 adults with hepatitis B, some with kidney disease and some healthy. Researchers measure how much drug gets into the blood and how long it stays. The goal is to see if kidney problems change drug levels, which could affect futur…
Phase 1 • Sponsor: GlaxoSmithKline • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
-
Massive ecuador study seeks clues to diabetic kidney damage
Knowledge-focused PausedThis study looks at over 10,000 adults in Ecuador to understand why some people with diabetes develop kidney disease. Researchers will collect health surveys, blood and urine samples, and kidney tissue to study social, environmental, and biological factors. The goal is to find ne…
Sponsor: Universidad Estatal de Milagro • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
-
Can shedding pounds protect kidneys? new study investigates
Knowledge-focused OngoingThis study looks at whether losing weight over two years can improve how the kidneys use oxygen and how the body responds to insulin in people with autosomal dominant polycystic kidney disease (ADPKD) who are overweight. Researchers will use PET scans and insulin tests to measure…
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
-
Can a 'Learning health System' help thailand tackle its chronic disease crisis?
Knowledge-focused OngoingThis study tests whether a Learning Health System (LHS) can improve care for people with high blood pressure, diabetes, and kidney disease in Thai primary care clinics. The LHS uses electronic health records to help healthcare teams identify patients who need more active manageme…
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
-
Hidden heart and kidney disease: 16,660 people screened in major spanish study
Knowledge-focused OngoingThis study screened over 16,600 adults aged 45-70 with at least one risk factor (like high blood pressure or smoking) but no known heart disease. Researchers used ultrasound and simple blood and urine tests to find hidden signs of atherosclerosis, pre-diabetes, and kidney disease…
Sponsor: Institut de Recerca Biomèdica de Lleida • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
-
3,000 haitians join Long-Term heart health study
Knowledge-focused OngoingThis study follows about 3,000 adults in Port-au-Prince, Haiti, to learn how common heart disease risk factors like high blood pressure, diabetes, and smoking are, and how they lead to heart attacks, strokes, and other heart problems. Researchers will track participants for about…
Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
-
New digital tool aims to cut medical errors during hospital transfers
Knowledge-focused By invitation onlyThis study tests a new digital platform that helps doctors and nurses share important patient information when a person is moved from one hospital to another. About 1,000 adults being transferred to a major hospital will take part. The goal is to see if better information sharing…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
-
App aims to boost follow-up rates for living kidney donors
Knowledge-focused OngoingThis study looks at whether a mobile health app can help living kidney donors complete their required follow-up visits after donating a kidney. About 400 donors will be randomly assigned to use the app or receive standard care. The goal is to see if the app improves compliance wi…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
-
Social media may help kidney patients find donors
Knowledge-focused OngoingThis study tests whether an educational program and a mobile health app can help adults with kidney failure find a living donor for a transplant. About 775 participants who haven't yet identified a donor will take part. The goal is to see if these tools increase the number of liv…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
-
Withdrawn study sought safer biopsies for Bleeding-Prone patients
Knowledge-focused CancelledThis study planned to test a technique called radiofrequency track cautery during liver, kidney, or spleen biopsies in patients at high risk for bleeding. The idea was to use a small heated probe to seal the biopsy track and reduce bleeding. However, the study was withdrawn befor…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
-
Kidney disease linked to faster memory loss, new study aims to find out why
Knowledge-focused OngoingThis study follows 600 people with and without chronic kidney disease (CKD) for up to four years to compare how often memory loss, confusion, and daily activity problems occur. Researchers will also look for risk factors that make thinking and memory worse in CKD patients. Partic…
Sponsor: Anne Murray • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
-
Plant protein swap may cut heart & diabetes risk – but how much?
Knowledge-focused OngoingThis study is a review of many smaller trials that looked at what happens when people replace animal protein (like meat, dairy, eggs) with plant protein (like beans, nuts, seeds). The goal is to see if this simple swap can improve blood sugar, cholesterol, blood pressure, weight,…
Sponsor: John Sievenpiper • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
-
300 volunteers help create medical image bank for science
Knowledge-focused OngoingThis study gathers MRI, CT, and ultrasound images from 300 adults—some healthy, some with kidney or brain disease—to build a collection for future not-for-profit research. No new treatments are being tested; the goal is to make medical images available to scientists for advancing…
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:28 UTC
-
Massive study seeks genetic clues to protect black HIV patients from organ damage
Knowledge-focused OngoingThis study follows over 3,000 Black people with HIV in the UK to understand how genes and lifestyle affect their risk for kidney disease, heart disease, diabetes, and obesity. Researchers collect health data and blood/urine samples to find genetic markers that predict these condi…
Sponsor: King's College Hospital NHS Trust • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:23 UTC