Hidden heart and kidney disease: 16,660 people screened in major spanish study
NCT ID NCT03228459
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study screened over 16,600 adults aged 45-70 with at least one risk factor (like high blood pressure or smoking) but no known heart disease. Researchers used ultrasound and simple blood and urine tests to find hidden signs of atherosclerosis, pre-diabetes, and kidney disease. The goal is to learn what factors contribute to these hidden conditions and whether early detection can reduce future heart attacks and deaths.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify hidden risk factors for heart and kidney disease in seemingly healthy people, leading to better prevention strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly change patient outcomes, and results may not apply to other populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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16,660 people
The number who actually took part.
- Started
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Jan 2015
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * women (50-70 years) and men ( 45-65 years) with at least one cardiovascular risk factor (hypertension, dyslipidemia, obesity (BMI \>30 Kg/m2), current smoking habit or former smoker (\<10 years), first-degree family history of early cardiovascular disease). Exclusion Criteria: * Prior medical history of cardiovascular disease. * Diabetes. * Glomerular filtration rate (CKD-EPI \< 60 ml/min/1.73m2). * Active neoplasm or acute disease. * A life expectancy \< 18 months. * Pregnancy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fundació Renal Jaume Arnò
Lleida, Lleida, 25006, Spain
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Institut de recerca Biomèdica de Lleida
Lleida, Lleida, 25198, Spain
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Primary Care centre
Lleida, Lleida, 25007, Spain
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