Circadian rhythm sleep disorder

This study looked at 61 night workers aged 20-55 to understand how their sleep patterns relate to attention and heart rate. Participants took ramelteon (Rozerem), a drug similar to melatonin, for two weeks. Researchers measured changes in sleep quality, anxiety, and depression us…

This study is testing whether special drug-free patches can help relieve acute back, shoulder, or other muscle pain and improve sleep. The patches use a gentle vibration technology instead of medication. 150 adults aged 18-64 will wear either an active patch or a sham (fake) patc…

This study tested whether a herbal supplement called Redormin 500 (made from valerian and hop extracts) can help people with occasional sleep problems think more clearly during the day and feel better overall. Forty healthy adults with mild sleep issues took either the supplement…

This study tested whether a desk lamp that gives off near-infrared light can help people who feel sleepy or down during the day. Eighty healthy adults aged 25 to 65 used the lamp at their desk for two weeks. Researchers checked changes in mood, drowsiness, sleep quality, and bloo…

This study looked at whether exercising in the morning or evening helps control blood sugar better in pregnant women with gestational diabetes or glucose intolerance. 39 women walked or stepped for 30 minutes either after breakfast or after dinner. The researchers measured blood …

This small study tested whether wearing bright light glasses each morning could improve symptoms of irritable bowel syndrome (IBS) and reduce leaky gut. Five adults with IBS used the light device for two weeks. The goal was to see if the light therapy eases belly pain, bloating, …

This study tested whether the drug Lemborexant helps people with delayed sleep phase syndrome (a condition where your natural sleep time is much later than desired) fall asleep faster. 71 adults took either the drug or a placebo nightly for up to 2 years. The main goal was to see…

This study tested whether installing special LED lights that mimic sunlight in hospital rooms could help treat depression and improve sleep. Fifteen adults with major depression participated. The goal was to see if the lights were comfortable and if they could reduce depression s…

This study tested whether wearing a light-blocking eye mask at night (11 p.m. to 5 a.m.) could improve sleep quality and melatonin levels in 60 intensive care unit patients. Participants were randomly assigned to either wear the mask or receive standard care. Sleep quality was me…

This study tested whether an Apple Watch paired with a special app and weekly health coaching could help dementia caregivers improve their sleep and mood. Twenty-one caregivers wore the watch to track their activity and sleep, and received personalized feedback and motivational c…

This study tested a non-drug treatment called Personalized Integrated Chronotherapy (PIC) for depression during pregnancy and after childbirth. 120 pregnant women with major depression were randomly assigned to receive either usual care (medication or therapy) or PIC plus usual c…

This study tested a sleep and circadian treatment (TranS-C) for people with severe mental illness (SMI) in community mental health centers. The treatment was adapted to better fit these settings. Researchers looked at whether it improved sleep, daily functioning, and symptoms in …

This study tested two versions of a sleep treatment for people with severe mental illness in community mental health centers. One version was the standard treatment, and the other was adapted to better fit patients' needs. The goal was to see if training clinic staff to deliver t…

This study looked at whether adding special breathing muscle training to running programs helps 10-13-year-old male football players improve their agility, endurance, and lung function. 75 boys who had played football for at least two years took part. The training was tailored to…

Researchers want to know if exercising in the morning or evening changes physical performance and blood markers in healthy young male soccer players. Eight participants complete the same jump and shuttle-run tests twice, once in the morning and once in the evening, with a four-da…

This study tested whether bright light in the afternoon, alone or with morning light, can shift teens' internal body clocks earlier. 84 adolescents aged 18-20 followed a stable sleep schedule and then lived in a lab for a week. Researchers measured melatonin levels to track clock…

This study aims to translate and validate a French version of the Sleep Regularity Questionnaire (SRQ), a tool that measures how consistent a person's sleep schedule is. Researchers will enroll 50 adults with chronic insomnia or circadian rhythm disorders, who will fill out the q…

This study looked at whether people with binge eating disorder have a disrupted body clock. Researchers compared 43 adults with and without the condition, measuring melatonin levels and activity patterns. The goal was to understand how the circadian system might be involved, whic…

This study tested whether taking salt with breakfast versus dinner changes blood pressure patterns and nighttime salt excretion in 53 obese adults. Participants took salt tablets at different times of day. The goal was to see if timing affects blood pressure rhythms and related h…

This study tests whether a very short sleep survey, called the Sleep Vital Sign, can help primary care doctors recognize sleep disorders like sleep apnea, insomnia, and restless leg syndrome. About 1,260 adults visiting their Kaiser Permanente doctor will fill out the survey, whi…

This study looks at how sleep and body clock disruptions impact the brain's reward and impulse control systems in teenagers. Researchers will monitor sleep, brain activity, and decision-making in 100 healthy high school students. The goal is to understand why poor sleep may incre…

This study looks at whether a 90-minute afternoon nap, a moderate dose of caffeine, and a short recovery routine (stretching plus a snack) can improve evening athletic performance. Sixty elite university athletes (30 men, 30 women) will try different combinations of these strateg…

This study looks at how not getting enough sleep and being awake at odd hours affects your thinking, blood chemistry, and the helpful bacteria in your gut. Researchers gave 55 healthy adults a prebiotic supplement or a placebo to see if it could help counter the negative effects.…

This study tested whether eating 28 grams of pistachios (about 40 nuts) one hour before bedtime could help regulate the body's internal clock in 28 overweight young adults. Researchers measured melatonin levels, antioxidant activity, and sleep-wake patterns. The goal was to see i…

This study followed 59 nurses during their first year of work to see if night shifts harm bone health. Researchers measured bone density and markers of bone turnover in night shift nurses compared to day shift nurses. The goal was to understand if shift work increases the risk of…

This completed study in Norway looked at whether delaying school start times by one to two hours on Mondays and Tuesdays helps high school students sleep longer, feel less sleepy during the day, and improve their mental health and grades. Over 580 first-year students participated…

This study tested a computer system designed to help doctors more accurately diagnose and manage complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected health data from 635 people visiting specialty clinics, including healthy volunteers, to see…

This pilot study tested whether limiting food intake to an 8am-to-6pm window for four weeks could improve metabolic health and appetite regulation in 16 healthy adults. Participants ate freely during that window and fasted the rest of the time. The study measured changes in appet…

This study looked at how the sleep hormone melatonin and a specific gene (MTNR1B) work together to control blood sugar. Researchers tested 23 healthy adults in a controlled lab setting. The goal was to understand why some people may have higher diabetes risk, which could lead to …

This completed study looked at how blood sugar levels affect sleep in 30 adults with cystic fibrosis-related diabetes. Participants wore devices at home to track glucose and sleep for 10 days. The goal was to see if this kind of remote monitoring is practical and to gather early …

This study looked at 200 heart transplant patients to see if the time of day the donor heart was removed affects how well the patient does. Researchers compared hearts taken during the body's rest phase (midnight to noon) versus the active phase (noon to midnight). They tracked s…

This study looked at whether working night shifts for just three nights in a row can disrupt bone health. Twenty healthy adults aged 20-40 either followed a normal sleep schedule or stayed awake at night and slept during the day. Researchers measured bone turnover markers to see …

This study looked at how the timing of sleep affects what teenagers eat. Researchers wanted to understand why getting more sleep helps some teens eat less, but not others. They studied 190 healthy teens aged 14-18 to see if matching sleep to their natural body clock improves thei…

This study looked at how lack of sleep and evening light exposure affect the body clocks of teenagers aged 14 to 17. Researchers used morning bright light to try to shift teens' sleep schedules earlier. They measured changes in melatonin levels and sleep patterns to understand wh…