Weight loss showdown: surgery vs diet before knee or hip replacement

NCT ID NCT05156762

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to see if bariatric surgery or medical weight loss (diet and exercise) helps severely obese patients lose enough weight to safely undergo hip or knee replacement. Only 3 people took part before the study was stopped early. The goal was to get patients to a BMI of 40 or lower before surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bariatric surgery (sleeve gastrectomy or gastric bypass) and medical weight loss (diet, exercise, counseling)

What this could lead to

If successful, this could show that weight loss before joint replacement improves surgical outcomes and reduces complications.

What could go wrong

The trial was terminated early with only 3 participants, so results are very limited. Weight loss may not be enough to improve joint replacement outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

morbid obesity osteoarthritis, hip osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States