Teen diabetes risk linked to immune cells, new study suggests

NCT ID NCT06007404

Recruiting now Knowledge-focused Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study looks at how certain immune cells, called meta-inflammatory monocytes, along with body composition and diet, may contribute to insulin resistance in adolescents. Researchers will collect blood samples and health information from 175 teens aged 14-18, including those with normal weight, overweight, obesity, or type 2 diabetes. The goal is to better understand the early steps that lead to metabolic disease, which could help develop future prevention strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward new ways to predict or prevent type 2 diabetes in teenagers.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test any therapy, and results may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance metabolic disease Obesity obesity disorder prediabetes syndrome type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INSULIN RESISTANCE METABOLIC DISEASE OBESITY PREDIABETES TYPE 2 DIABETES

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States

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