Could a natural compound help aging hearts? new trial investigates spermidine

NCT ID NCT06186102

First seen Nov 18, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tests whether spermidine, a natural substance found in foods like wheat germ and soy, can improve heart and muscle health in people aged 65 and older with coronary artery disease. About 180 participants will receive either spermidine or a placebo for a period, and researchers will measure changes in heart mass, muscle mass, inflammation, and exercise capacity. The goal is to see if this simple dietary supplement can help manage heart disease and related conditions like obesity and diabetes.

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Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, Jutland, 8200, Denmark

Conditions

Explore the condition pages connected to this study.