New combo therapy targets Hard-to-Treat cancers in early trial
NCT ID NCT03983954
First seen Jan 04, 2026 · Last updated Apr 30, 2026 · Updated 15 times
Summary
This early-phase trial tests a combination of two drugs, naptumomab estafenatox and durvalumab, in adults with advanced solid tumors that have not responded to standard treatments. The main goal is to find a safe dose and check for side effects. About 120 people with various cancers, including breast, ovarian, and lung cancer, are taking part.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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All India Institute of Medical Sciences
New Delhi, New Delhi, 110029, India
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Basavatarakam Indo-American Cancer Hospital & Research Institute
Hyderabad, Telangana, 500034, India
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National Cancer Institute
Jhajjar, Haryana, 124105124105, India
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PMCH (Pacific Medical College & Hospital)
Udaipur, Rajasthan, 313001, India
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Rabin Medical Center
Petah Tikva, Israel
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Rambam Medical Center
Haifa, 3109601, Israel
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Shalby Hospital
Ahmedabad, Gujarat, 380015, India
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Sheba Medical Center
Ramat Gan, 52621, Israel
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Tel Aviv Sourasky Medical Center
Tel Aviv, 6423906, Israel
Conditions
Explore the condition pages connected to this study.