ER+ BREAST CANCER

This study is testing whether giving hormone therapy before surgery helps women with a specific type of breast cancer have better surgical outcomes. Researchers want to see if this approach reduces the chance that cancer cells are left at the edges of removed tissue, which often …

This study is testing whether giving radiation treatment a second time is safe for women whose breast cancer has returned in the same breast. Researchers want to understand both the benefits and risks of this approach for patients who have already had radiation therapy. The study…

This study is testing a new oral drug called ETX-19477 in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see if the drug can help control the cancer. Researchers are especially interested in enroll…

This study is testing if using highly focused radiation on a single tumor that has started growing again can help people with metastatic breast cancer stay on their current effective drug treatments longer. Participants will receive this targeted radiation while continuing their …

This study is testing several combination treatments involving the experimental drug FWD1802 for people with advanced ER-positive/HER2-negative breast cancer that has spread or cannot be removed by surgery. The research aims to find safe doses and see if these combinations can he…

This study is testing whether a medication called elacestrant can prevent breast cancer from coming back years after initial treatment. It focuses on patients with ER+ breast cancer who have tiny amounts of cancer DNA circulating in their blood but no visible cancer on scans. The…

This early-stage study is testing a new oral medication called JAB-2485 in adults with advanced solid tumors that have stopped responding to standard treatments. Researchers will first determine the safest dose and then look for early signs that the drug can shrink tumors in spec…

This small, early-phase study is testing a new approach for patients whose metastatic breast cancer has become resistant to standard hormone therapy due to a specific gene change (ESR1 mutation). Researchers will use a special imaging scan (FES-PET/CT) to see how well the drug ta…

This study is testing a new decision-making tool for women aged 70 and older who have a common, low-risk type of early breast cancer. The goal is to see if giving patients a detailed guide and training their surgeons in shared decision-making leads to fewer aggressive treatments …

This early-stage study is testing the safety and effectiveness of combining two drugs, palbociclib and avelumab, for patients with advanced breast cancer. It focuses on a specific, hard-to-treat type called AR-positive triple-negative breast cancer. The goal is to see if this new…