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New PET tracer could reveal hidden breast cancer throughout the body

NCT ID NCT04824014

Recruiting now Diagnosis Sponsor: Centre de recherche du Centre hospitalier universitaire de Sherbrooke Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This phase 2 trial tests a new radioactive tracer called 4FMFES for PET scans in people with advanced estrogen receptor positive (ER+) breast cancer. The tracer binds to estrogen receptors, allowing doctors to see where the cancer has spread anywhere in the body. The study aims to see if combining 4FMFES-PET with standard FDG-PET gives a more complete picture of the disease, helping guide treatment decisions and predict outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
4FMFES (a radioactive tracer for PET imaging)
What this could lead to
If successful, this imaging method could become a standard tool for whole-body assessment of estrogen receptor status, helping doctors choose the best treatment for advanced breast cancer without repeated biopsies.
What could go wrong
This is a phase 2 trial with 150 participants, so it is still early. The tracer may not prove superior to existing methods in real-world use, and its availability may be limited.

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Conditions

The condition(s) this trial relates to.

estrogen-receptor positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ERΑ+ BREAST CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Université deSherbrooke

    RECRUITING

    Sherbrooke, Quebec, J1H5N4, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

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