New drug combo shows promise for Hard-to-Treat breast cancer
NCT ID NCT04920708
First seen Apr 23, 2026 · Last updated May 15, 2026 · Updated 5 times
Summary
This phase 2 study tests whether adding the experimental drug ipatasertib to standard hormone therapy and a targeted drug can help people with a specific type of advanced breast cancer (ER+/HER2-) live longer without their cancer growing. The study includes 57 participants whose cancer did not respond well to initial treatment. Researchers use a blood test to track cancer DNA and guide treatment decisions.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Addenbrookes Hospital
Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
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Beatson West of Scotland Cancer Centre
Glasgow, United Kingdom
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Imperial College University Hospitals NHS Trust
London, W2 1NY, United Kingdom
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Mount Vernon Cancer Centre
London, Surrey, HA6 2RN, United Kingdom
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Nottingham City Hospital
Nottingham, United Kingdom
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Oxford University Hospitals
Oxford, OX3 7LE, United Kingdom
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Royal Cornwall Hospital
Truro, Cornwall, TR1 3LQ, United Kingdom
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Royal Free Hospital
London, NW3 2QC, United Kingdom
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Royal Marsden NHS Foundation Trust
London, SW3 6JJ, United Kingdom
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The Christie NHS Foundation Trust
Manchester, M20 4BX, United Kingdom
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University College London Hospital
London, United Kingdom
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Velindre Cancer Centre
Cardiff, Wales, CF14 2TL, United Kingdom
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Western General Hospital
Edinburgh, EH4 2XU, United Kingdom
Conditions
Explore the condition pages connected to this study.