New drug combo offers hope for kids with Tough-to-Treat cancers

NCT ID NCT06607692

First seen Apr 17, 2026 · Last updated Jun 18, 2026 · Updated 5 times

Summary

This study is for children and teens (ages 3 to 18) with certain solid tumors that have returned or not responded to standard treatment. The tumors must have a specific marker called SSTR. The study combines two drugs: Lutathera (a radioactive drug that targets SSTR) and Olaparib (a pill that may make cancer cells more sensitive to radiation). The goal is to find the safest dose and see if the combination can shrink tumors. About 25 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • HM Monteprincipe

    RECRUITING

    Boadilla del Monte, Madrid, 28660, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

adrenal carcinoma adrenal cortex neoplasm adrenal gland cancer adrenal gland neoplasm cancer diffuse intrinsic pontine glioma ependymoma esthesioneuroblastoma Esthesioneuroblastoma, Olfactory glioblastoma glioma malignant glioma medulloblastoma meningioma neuroblastoma neuroendocrine neoplasm osteosarcoma paraganglioma pheochromocytoma pheochromocytoma-paraganglioma Recurrence refractory malignant neoplasm synovial sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.