MEDULLOBLASTOMA RECURRENT
Clinical trials for MEDULLOBLASTOMA RECURRENT explained in plain language.
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Promising combo targets Hard-to-Treat childhood cancers
Disease control Recruiting nowThis study is testing a combination of two drugs—a targeted radioactive drug (177Lu-DOTATATE) and a PARP inhibitor (olaparib)—in children and teens aged 3 to 18 with certain solid tumors that have come back or not responded to treatment. The goal is to see if the combination is s…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1, PHASE2 • Sponsor: Fundación de investigación HM • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Killer virus turned against childhood brain cancer
Disease control Recruiting nowThis early-stage trial tests whether a specially engineered herpes virus (G207) is safe to inject directly into the brain tumors of children whose cancer has returned. Up to 24 children aged 3 to 21 will receive the virus, and some will also get a small dose of radiation to help …
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New hope for kids with tough brain tumors: gene therapy meets immunotherapy and radiation
Disease control Recruiting nowThis early-phase trial is testing a combination of three treatments for children whose brain tumors have come back or not responded to standard care. The experimental drug SGT-53 delivers a normal TP53 gene to tumor cells, and is given alongside the immunotherapy Nivolumab and ra…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: EARLY_PHASE1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Promising combo therapy offers hope for kids with hard-to-treat brain cancers
Disease control Recruiting nowThis study tests a combination of drugs given in low, frequent doses to slow or stop the growth of recurrent brain tumors in children. The goal is to extend survival while maintaining quality of life. About 232 children with medulloblastoma, ependymoma, ATRT, or other rare CNS tu…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE2 • Sponsor: Medical University of Vienna • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Tailored tumor testing aims to match kids with best brain cancer therapy
Knowledge-focused Recruiting nowThis study is testing a new approach for children and young adults whose medulloblastoma or ependymoma has come back. Researchers will analyze each person's tumor using drug screening and genetic testing to create a personalized treatment plan. The goal is to find the most effect…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Brain tumor biobank aims to unlock secrets of rare genetic mutation
Knowledge-focused Recruiting nowThis study is building a biobank of blood, tissue, and health information from 300 children and adults with relapsed or hard-to-treat sonic hedgehog medulloblastoma, a type of brain tumor. Researchers want to learn more about a specific genetic mutation called U1, which may affec…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Sponsor: Mohammad H. Abu Arja • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC