Brain tumor biobank aims to unlock secrets of rare genetic mutation
NCT ID NCT07242963
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is building a biobank of blood, tissue, and health information from 300 children and adults with relapsed or hard-to-treat sonic hedgehog medulloblastoma, a type of brain tumor. Researchers want to learn more about a specific genetic mutation called U1, which may affect how the tumor grows and responds to treatment. Participants will not receive direct treatment, but their samples could help develop better therapies in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help researchers design better treatments for relapsed SHH medulloblastoma by understanding the U1 mutation.
- What could go wrong
- This is an observational registry, not a treatment trial. It will not directly benefit participants and may not lead to new therapies for years.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77004, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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