MEDULLOBLASTOMA RECURRENT
Clinical trials for MEDULLOBLASTOMA RECURRENT explained in plain language.
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New hope for kids with brain cancer: triple therapy trial launches
Disease control Recruiting nowThis early-phase trial tests a new drug (SGT-53) combined with radiation and immunotherapy (Nivolumab) in up to 18 children whose brain tumors have returned or not responded to standard treatments. The main goal is to find a safe dose and understand side effects. It is not a cure…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: EARLY_PHASE1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated May 17, 2026 03:00 UTC
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Promising combo therapy for childhood cancers enters human trials
Disease control Recruiting nowThis study tests a combination of two drugs—Lutathera (a targeted radiation therapy) and olaparib (a PARP inhibitor)—in children and teens aged 3 to 18 with solid tumors that have come back or not responded to standard treatment. The goal is to find the safest dose and see if the…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1, PHASE2 • Sponsor: Fundación de investigación HM • Aim: Disease control
Last updated May 17, 2026 03:00 UTC
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Promising combo therapy offers hope for kids with rare brain cancers
Disease control Recruiting nowThis study tests a combination of low-dose chemotherapy and targeted drugs to control recurrent brain tumors in children. The goal is to extend survival while maintaining a good quality of life. About 232 children with medulloblastoma, ependymoma, ATRT, or other rare CNS tumors w…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE2 • Sponsor: Medical University of Vienna • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Virus therapy takes on childhood brain cancer in new trial
Disease control Recruiting nowThis early-stage trial tests a specially engineered virus, G207, in children and young adults whose cerebellar brain tumors have come back or not responded to standard treatments. The virus is injected directly into the tumor, and a single low dose of radiation is given to help t…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 04, 2026 16:21 UTC
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Brain tumor biobank aims to unlock genetic secrets for better treatments
Knowledge-focused Recruiting nowThis study creates a biobank for children and adults with a relapsed or hard-to-treat type of brain tumor called sonic hedgehog medulloblastoma that has a specific genetic change (U1 mutation). Researchers will collect medical records, tumor samples, and optional cheek swabs from…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Sponsor: Mohammad H. Abu Arja • Aim: Knowledge-focused
Last updated May 17, 2026 03:09 UTC
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Tailored tumor testing aims to match kids with best drugs
Knowledge-focused Recruiting nowThis study is testing a new approach for children and young adults whose medulloblastoma or ependymoma has come back. After surgery, the tumor is quickly tested in the lab and its genes are analyzed to find the most effective and least toxic drugs for that specific patient. A spe…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC