MEDULLOBLASTOMA RECURRENT
Clinical trials for MEDULLOBLASTOMA RECURRENT explained in plain language.
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Sound waves open brain barrier to deliver cancer drug in kids
Disease control Not yet recruitingThis early-stage trial tests whether using focused ultrasound with microbubbles can temporarily open the blood-brain barrier, allowing the immunotherapy drug nivolumab to reach brain tumors more effectively. It includes 30 children and young adults with relapsed diffuse midline g…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New hope for kids with aggressive brain cancer: hormone therapy plus chemo
Disease control Not yet recruitingThis study tests a thyroid hormone called liothyronine (L-T3) alone or with standard chemotherapy in children and young adults whose medulloblastoma has come back or worsened. The goal is to see if adding L-T3 can help control the cancer better. About 69 participants will take pa…
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1, PHASE2 • Sponsor: Sabine Mueller, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Immune cells engineered to fight brain cancer in kids
Disease control Not yet recruitingThis early-phase study tests the safety of a new cell therapy called B7-H3 CAR T cells for children and young adults whose brain tumors have come back or are growing despite standard treatment. The therapy uses the patient's own immune cells, modified to target a protein (B7-H3) …
Matched conditions: MEDULLOBLASTOMA RECURRENT
Phase: PHASE1 • Sponsor: Robbie Majzner • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC